Place of Origin: | China |
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Brand Name: | YW |
Certification: | GMP,SGS,BV,ISO |
Model Number: | 1379686-29-9 |
Minimum Order Quantity: | 10gram |
Price: | Negotiable |
Packaging Details: | Disguised package &Foil bag or according to customs need |
Delivery Time: | Within 24 hours after payment |
Payment Terms: | T/T, Western Union, MoneyGram,Bitcoin |
Supply Ability: | 1000kg/Month |
CAS: | 1379686-29-9 | Character: | White Powder |
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Purity: | 99.5% | Usage: | Bodybuilding&athletes Competition |
MF: | C23H31ClN4O3S | MW: | 479.03524 |
High Light: | raw sarm powder,muscle building sarms |
Muscle building SARMS SR9011 powder CAS 1379686-29-9 for endurance training
Product name:SR9011
Synonyms:SR9011;SR9001;3-[[[(4-Chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide
CAS:1379686-29-9
Purity: 99% by HPLC.
MF:C23H31ClN4O3S
Molar mass: 479.03524 g/mol
Character:white powder
SR9011 Powder Storage: 4°C for 1 year.
SR9011 Solubility: In Ethanol approx. 14mg/ml, in DMSO and Dimethyl formamide (DMF) approx. 30mg/ml.
Package:50gram / foil bag
Shelf life: 2 years
SR9011 Description
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
SR 9011 (Powder) Effects.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
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Commerce Clause
Minimum Order Quantity: | 10-100g.as for oil steroids , MOQ is 50ml |
Price: | Negotiable |
Payment Terms: | Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin |
Packaging Details: | Discreet and Disguised packing |
Delivery time: | Within 12 hours after receiving the payment |
Leading time: | 4~6 working days after confirming the payment |
Delivery | By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door)bulk order can be negotiable |
Tracking number | can be offered to you within 24h |
Supply Ability: | Mass in stock |
FAQ
Question 1 , How do you pack the order ?
Discreet package , the packing suits you best would be choosen to cross customs safely
Question 2 , What is your shipping method ?
Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail
Question 3 , if my order seized by custom ,what do you do ?
Resending police if the tracking number do not update online or it sezied by custom
Questions 4 , What is your payment accept ?
Safe and fast payment :Western Union ,Money Gram ,T/T ,Bitcoin
Questions 5 , Will you supply tracking number ?
Yes ,we supply tracking number for following .In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days
Question 6 , How many days will it take to my country after I do the payment ?
In general ,fastest with 3-5 business , slowest 5-7 business days
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