Anti-inflammatory Drug Mometasone Furoate CAS: 83919-23-7 White Powder
Mometasone Furoate is the furoate salt form of mometasone, a synthetic topical glucocorticosteroid receptor agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Mometasone furoate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2.
Chemical name: MOMETASONE FUROATE
Purity: over 99%
Appearance: white powder
Package: 1KG foil bag
Usage: anti-inflammatory agent
|Product name||Mometasone Furoate|
|CAS No.||83919-23-7||Outer Packing||1KG|
|Production date||2017.11.15||Shelf life||2019.11.14|
|Items of analysis||Specification||Results|
|Description||White to off-white powder||Conform|
|Melt Point||About 220℃||220.5℃|
|Specific Rotation||+56 －+62 °||+58.4°|
|Loss on drying||≤0.5%||0.31%|
|Residue On Ignition||≤ 0.1%||0.08%|
|Heavy Metals||≤30 ppm||Conform|
Mometasone furoate is used in the treatment of inflammatory skin disorders (such as eczema and psoriasis) (topical form), allergic rhinitis (such as hay fever) (topical form), asthma (inhalation form)for patients unresponsive to less potent corticosteroids, and penile phimosis.In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.
Some low-quality evidence suggests the use of mometasone for symptomatic improvement in children with adenoid hypertrophy.
Mometasone is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis.
Nasal mometasone is used in adults (including the elderly) and children over two years of age, to diminish the symptoms such as hay fever (seasonal allergic rhinitis) and other allergies (perennial rhinitis), including nasal congestion, discharge, pruritus, and sneezing and to treat nasal polyps.
How to use Mometasone FUROATE Ointment?
Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is for use only on certain areas of skin: do not use it on the face, groin, or underarms, or for diaper rash, unless directed to do so by your doctor.
Wash and dry your hands before using. Clean and dry the affected area. Apply as directed by your doctor, usually a thin film of medication to the affected area once daily. Gently rub in. Do not cover the treated area with bandages or other dressings unless instructed to do so by your doctor. If used near the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
Do not wash or rinse the medication off immediately after applying it. Wash your hands with soap and water after each use unless you are using this medication to treat the hands. Avoid getting this medication in your eyes, nose, or mouth. If this occurs, rinse thoroughly with water and call your doctor if irritation persists.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Do not apply large amounts of this medication, use it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects may increase.
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