GBL Colorless transparent liquid Gamma-Butyrolactone Safe Organic Solvent Medicine Intermediate CAS:96-48-0
GBL is an important chemical raw material and intermediate for medicine, and also the intermediate of the synthesize N-methyl pyrrolidone, α -pyrrolidone, polyvinyl pyrrolidone, α -acetyl-γ -butyrolactone, methionine and the butyric acid compounds.
This product features a strong solubility, and is a good solvent for polyacrylonitrile, epoxy resin, polyvinyl butyral, polyvinyl chloride and its copolymers, and cellulose polymers. In medical industry, it is mainly used in synthesizing cyclopropylamine, etc.
Gamma butyrolactone (GBL) is a chemical compound that can be synthesized in laboratories but can also be found in unadulterated wines. On its own, gamma butyrolactone does not have any effects.Nevertheless, when it is absorbed into the blood, it is subjected to the action of lactonase enzymes. These enzymes catalyze the conversion of gamma butyrolactone into gamma hydroxybutyric acid (GHB).
As a prodrug of GHB, gamma butyrolactone is sometimes referred to as dehydrated GHB. As indicated by the term " dehydrated," GBL does not contain as much water as GHB, and is therefore more fat-loving, or lipophilic. Compared with GHB, GBL is absorbed faster when consumed with food. This causes it to produce the desired effects faster. The duration of action of gamma butyrolactone, however, is also shorter than that of its counterpart.
The effects of gamma butyrolactone are based on its property as a prodrug of GHB. GHB is similar to the naturally produced neurotransmitter called gamma aminobutyrate (GABA). GABA is produced by the brain and acts on receptors to block nerve impulses, thereby earning the label " inhibitory" neurotransmitter. The effects of GABA include relaxation, sleep, an increased feeling of well-being, decreased anxiety and decreased muscle tone. Furthermore, GABA release is associated with increased levels of growth hormone.
Product name :Gamma-Butyrolactone,GBL
Synonyms:1-Oxacyclopentan-2-one;2(3H)-dihydrofuranone;Gamma Butyrolactone, 1, 4- Butyrolactone,;γ -Butyroladone,;GBL; BLO,
Melting point: -45℃
Appearance:Colorless transparent liquid
Usage: Used as pharmaceutical intermediate, industry solvent, diluents, curing agent.
|Appearance||Colorless clear liquid||Colorless clear liquid|
|Purity (wt%, GC)||≥99.80||99.80|
|Moisture (wt%, K.F.)||≤0.03||0.020|
|Glycol (wt%, GC)||≤0.02||0.003|
|Tetrahydrofuran (wt%, GC)||≤0.03||0.024|
|Conclusion: It conforms to electron level|
It can be converted to GHB and can increase growth hormone levels, so gamma butyrolactone was widely marketed during the 1990s as a nutritional supplement. At low doses that range from 500-1,500 milligrams, the intake of GBL or GHB can promote relaxation.
At medium doses that range from 1,000-2,500 milligrams, the resulting muscle relaxation can give a person a decreased sense of balance and decreased coordination. At high doses, a person would experience adverse effects that include nausea; vomiting; decreased breathing rate, or bradypnea; decreased heart rate, or bradycardia; and seizures. The worst outcomes are coma and death.
Used to synthesize pyrrolidone products; Used as a pharmaceutical intermediate, such as Cyclopropylamine and vitamin;Used as a pesticide intermediate, such as herbicide and plant growth regulator;Used for alkenes, alkynes extraction agent, absorbent and dispersing agent;
Used to synthesize resin as an antioxidant, plasticizer, dispersing agent, fixing agent and solvent;Used to synthesize fiber spinning solvent, coagulant, dyeing assistant and antistatic agent; Used as a raw material of color film former, electrolyte, capacitor and ink lubricant.
1) Used to produce a-pyrrolidone, 1-Methyl-2-pyrrolidinone, polyvinyl pyrrolidone, and a -Acetyl-r -butyrolactone;
2) used as anaesthetic and tranquilizer, used to produce ciprofloxacin and interferon, as the intermediate of vitamin and rolicyprine;
3) As antioxidant, plasticizer, extractant, adsorbent, dispersant, fixative and curing agent;
4) Used in battery, capacitor and development of color film.
Despite serious safety concerns and illegality, people take gamma butyrolactone for improving athletic performance, sleep, and sexual performance and pleasure.
They also take it for relieving depression and stress, prolonging life, promoting clear thinking, causing relaxation, and releasing growth hormone. GBL is also used to trim fat and as a body- or muscle-builder. Some people take it as a recreational drug.
GBL is converted to GHB shortly after entering the body. Both produce a feeling of euphoria and can reduce inhibitions and cause sleepiness.
Gamma butyrolactone is a chemical. People use it as medicine. Be careful not to confuse gamma butyrolactone (GBL) with gamma hydroxybutyrate (GHB).
Gamma-Butyrolactone + NaOH => Sodium Gamma-Hydroxy Butyrate (Na-GHB).
1) GBL Magic Cleaner has a unique cleaning strength.
2) GBL is used to produce the related GHB. GHB has been classified as a Class C drug.
3) people take gamma butyrolactone (GBL) for improving sleep, athletic performance and sexual performance and pleasure.
They also take it for relieving depression and stress, promoting clear thinking, prolonging life, causing relaxation, and releasing hormone. GBL is also used to trim fat and as a body- or muscle-builder. Some people take it as a recreational drug.
The appropriate dose of gamma butyrolactone (GBL) depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for gamma butyrolactone (GBL).
Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
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