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Anti Estrogen Steroids Anastrozole for Bodybuilding CAS 50-41-9
Anastrozole is a drug used to treat breast cancer in post-menopausal women (women who have gone through the menopause/ change of life). Anastrozole is a type of hormone treatment known as an aromatase inhibitor. The female hormone oestrogen stimulates some breast cancers to grow. These are described as hormone sensitive or receptor positive tumours.
Post-menopausal women do continue to produce oestrogen.This is mostly produced when other hormones are converted into oestrogen by an enzyme known as aromatase, which is found in the liver and the fatty tissues of the body. Anastrozole works by stopping this conversion from taking place so that the amount of oestrogen circulating in the body is reduced.
Anastrozole has been tested for reducing estrogens, including estradiol, in men. Excess estradiol in men can cause benign prostatic hyperplasia, gynecomastia, and symptoms of hypogonadism. Anastrozole can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer.Some athletes and body builders use anastrozole as part of their steroid cycle to reduce and prevent symptoms of excess estrogen--gynecomastia, emotional lability and water retention.
Estradiol, the most potent form of estrogen, is produced in the body by aromatization of testosterone. This occurs via the aromatase enzyme. Because certain levels of estradiol are needed for men, some conversion of testosterone to estradiol is required. However, in two circumstances effective aromatase inhibition can give important benefits.
First, when an anabolic steroid cycle causes very aromatizable steroid levels and there is no control of the aromatase enzyme, conversion to estradiol becomes excessive. The resulting high estradiol can cause gynecomastia, water retention, depression, and/or loss of libido. It may also make it difficult to maintain a lean condition.
And second, some men have excessive estradiol levels even when not on an anabolic steroid cycle. This will act to decrease their natural testosterone production, and can also cause the above adverse side effects.
|Appearance||White crystalline powder|
Conform with standard IR
Conform with standard HPLC
|Solubility||Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile||Complies|
|Total Unspecified Impurity||max. 0.2%||0.06%|
|Individual unspecified impurlty||max. 0.1%||0.06%|
|Related compound B||max. 0.2%||0.06%|
|Related compound C||max. 0.2%||0.05%|
|Related compound D||max. 0.1%||0.06%|
|Related compound E||max. 0.1%||0.05%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.08%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32|
Anastrozol is a non-steroidalaromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women. The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor site.
An aromatase inhibitor. Used as an antineoplastic raw materials. Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer.
Anastrozol lowers the amount of oestrogen in the body. The female sex hormones oestrogen and progesterone stimulate many breast cancers to grow. Lowering the level of oestrogen can stop or slow the growth of breast cancer cells. Anastrozol blocks a process called aromatisation which changes sex hormones called androgens into oestrogen.This happens mainly in the fatty tissues, muscle and the skin and needs a particular enzyme called aromatase.
Take one 1 mg tablet of anastrozole each day, exactly as your doctor tells you to. Your dose will be printed on the label of the tablet pack to remind you.
You may take anastrozole at whatever time of day you find easiest to remember, but try to take your doses at the same time each day. This will help you to avoid missing any doses.
You can take the tablet before or after a meal.
If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
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