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CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity

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CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity

China CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity supplier
CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity supplier CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity supplier

Large Image :  CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity

Product Details:

Place of Origin: China
Brand Name: LSW
Certification: GMP, ISO9001, USP, KOSHER
Model Number: 62-44-2

Payment & Shipping Terms:

Minimum Order Quantity: 10 grams
Price: Negotiable
Packaging Details: Discreet disguised package or as required
Delivery Time: 3~7 working days
Payment Terms: Western Union, Moneygram, Bitcoin and Bank Wire Transfer
Supply Ability: 5000kg/week
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Detailed Product Description
Appearance: White Crystalline Powder Assay: 99%
Usage: Local Anesthetic Drug CAS Number: 62-44-2
MF: C10H13NO2 MW: 179.2157

CAS 62-44-2 Local Anaesthesia Drugs USA/Canada Warehouse Bulk Stock White painkiller Phenacetin 99% Purity
 
Description:
 

Phenacetin is a pain-relieving and fever-reducing drug,it is metabolized as paracetamol (acetaminophen), which replaced it in some over-the-counter medications following the ban on phenacetin.

 

Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.


Those who have taken drugs that contain phenacetin are more likely to develop cardiovascular disease, high blood pressure, anemia and cancer, and they are at a higher risk of death because of renal failure or diseases of the urinary system, according to various studies. A 1989 study showed that daily users of phenacetin were 5.1 times more likely to develop kidney disease than people who used the drug infrequently. The drug, which was also used in veterinary medicine, was shown to cause benign and malignant tumors in both mice and rats during experimental laboratory studies.

 

Some over-the-counter painkiller manufacturers replaced phenacetin with paracetamol, a similar drug that has not been shown to be a carcinogen. Paracetamol is also known as acetaminophen. Studies have shown that acetaminophen also can cause damage to the kidneys, but its side effects are not as serious as those of phenacetin.

 

Phenacetin, ( Phenacetin, or acetophenetidin ), chemical formula C10H13NO2, is a white crystalline solid at room temperature, melting point 134 ℃, is a by many countries to ban drugs. Phenacidine is a white, shiny flake crystal or white crystalline powder. The melting point of 137-138 ℃, the refractive index of 1.571. Insoluble in water, slightly soluble in ether, slightly soluble in boiling water, dissolved in ethanol and chloroform. When dissolved in concentrated sulfuric acid, it does not show color, and when it drops into the solution, it is orange. Odorless, bitter taste.

 
Quick Detail:
 
Name:Phenacetin
CAS: 62-44-2
EINECS Number: 200-533-0
Formula: C10H13NO2
MW: 179.2157
Density: 1.099g / cm3
Melting point: 133-138 ℃
Boiling point: 355.1 ° C at 760 mmHg
Flash Point: 168.5 ° C
Water-soluble: 0.076 g / 100 mL
Vapor Pressure: 3.21E-05mmHg at 25 ° C
Uses: Anti-inflammatory drugs
Assay: 99%
Appearance: White or almost white crystalline powder
 
COA:
 
Product name Phenacetin
CAS 62-44-2 Outer Packing 25KGS
Production date 2016.12.27 Shelf life 2019.12.26
Standard adopted BP68
Items of analysis Specification Results
Description Should comply with the standard Comforms
Identification Positive Positive
Melting point 134℃ to 136.5℃ 134.5℃ to 136.5℃
4-chloroacetanilide BP1968 <3.5ml/0.6g
P-Phenetidine BP1968 Comforms
Sulphated ash ≤0.1% 0.07%
Assay ≥99% 99.1%
Through a uss#80   98%
Conclusion Quality
 
Applications:
 
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).
 
It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.
 
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.
 
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CAS 62-44-2 Local Anaesthesia Drugs White Painkiller Phenacetin 99% Purity
 
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