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Pharmaceutical Raw Material Anti Estrogen Steroids Aromasin CAS107868-30-4

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Pharmaceutical Raw Material Anti Estrogen Steroids Aromasin CAS107868-30-4

China Pharmaceutical Raw Material  Anti Estrogen Steroids Aromasin CAS107868-30-4 supplier
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Product Details:

Place of Origin: CN
Brand Name: LSW
Certification: ISO9001,BRC,KOSHE
Model Number: 107868-30-4

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: Discreet pakcage
Delivery Time: 5-8 working days
Payment Terms: T/T, Western Union, MoneyGram,Bitcoin
Supply Ability: 5000kg/month
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Detailed Product Description
CAS: 107868-30-4 MF: C20H24O2
MW: 296.40 Packing: 25kg / Barrel
Assay: ≥ 99% Appearance: White Or Almost White Crystalline Powder

 
Pharmaceutical Raw Material and Intermedicate Anti Estrogen Exemestane Aromasin CAS107868-30-4,Breast Cancer Treatment
 
 
Basic information:
 
 
Chemical name: Exemestane,Aromasin
Product Category: Pharmaceutical raw materials and intermediates
Product content: ≥ 99%
CAS Number: 107868-30-4
Molecular formula: C20H24O2
Molecular Weight:296.40
Packing specifications: 25kg / barrel
Appearance: White or Almost White Crystalline Powder
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Assay(by HPLC): 98.0-101.2%min
Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds.
 
 
Abstract :
 
 
Exemestan is part of a general group of drugs called aromatase inhibitors. Normally in the body, some of the androgens (male hormones) that are made by the adrenal glands are converted to estrogen by an enzyme in fat tissue called aromatase. This drug blocks aromatase so that estrogen isn't formed that way. This lowers estrogen levels in women who do not have functioning ovaries. This drug doesn't affect estrog-en production from the ovaries, so has little effect on estrogen levels in women whose ovaries are working. If estrogen levels are lowered, breast cancers that require estrogen to grow may stop growing or even shrink.
 
Developed to help fight breast cancer, Aromasin is one of the most powerful estrog-en suppressing compounds available for body builders taking anabolic steroids. Additionally, it also raises testosterone in the body, which is a bonus for bodybuilders during post-cycle-therapy.
 
 
Aromasin (Exemestan) is one of those weird compounds that nobody really knows what to do with. It's a third generation Aromatase Inhibitor (AI) just like Arimidex (Anastrozol) and Femera (Letrozol).
 
 
Pharmaceutical Raw Material  Anti Estrogen Steroids Aromasin CAS107868-30-4
 
Descrition
 
Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.
 
The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.
 
 
Application
 
Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.
 
Exemestane is taken in tablet form once a day. Patients can experience side effects like nausea, anxiety, shortness of breath, abdominal pain, bone pain, and chest pain. Side effects vary widely between patients and patients should report the side effects they experience to their doctors, as some may be indicators of dangerous complications. Shortness of breath and chest pain in particular are causes for concern in patients taking exemestane.
 
 
COA:
 
TEST ITEMS SPECIFICATION RESULTS
Description : White Crystalline Powder White Powder
Identification : Positive Positive
Assay(by HPLC) : 98.0~102.0% 98.64%
Absorbance(E1cm) : 465~495 482.5
Melting Point : 191~195°C 193.5~195.0°C
Loss On Drying : 0.5%max 0.19%
Specific Rotation : +288°~ +298° +290.2°
Residue On Ignition : 0.1%max 0.03%
Related Substances : Total:1.5%max <1.3%
  Single:0.5%max <0.4%
Residue Solvents : 0.2%max 0.10%
Heavy Metals : 20PPm max <10PPm
Conclusion The specification conform with enterprise standard.
 
 
 
What is exemestan aromatase inhibitors bodybuilding steroids? How does exemestan aromasin works in bodybuilding?
 
Estrogen is an unwanted by-product of Steroid use. In some tissues of the male ody, there is a nasty little Enzyme called the "Aromatase" Enzyme. This Enzyme is esponsible for turning Testosterone and other male hormones into female ones like Estrogen, and Estradiol or other girly-like hormones. An abundance of Female ormones in the male body can cause a whole list of bad sideeffects, like male brea-st tissue growth and water retention. Bodybuilders use a lot of different drugs and ompounds to combat these bad side effects. The best way to keep Estrogen from causing problems is to make sure it is never created in high amounts in the first place. Using a compound that inhibits the Aromatas Enzyme is a sure way to make sure Testosterone and other Steroids are never onverted into side-effect causing Estrogen.
 
A compound that inhibit the Aromatase Enzyme from creating Estrogen is called an Aromatase Inhibitor, or AI for short. There are a lot of options out there when it comes to AI's (Aromatase Inhibitors), and Aromasin is certainly one of the most popular options for bodybuilders that cycle steroids for a number of reasons.
 
Aromasin is a suicidal Aromatase inhibitor, which makes it a better choice than other AIs. Exemestan binds with aromatase enzymes and then subsequently
permanently disables the enzyme by destroying it.
 
Aromasin is a steroidal AI which keeps it from negatively affecting your lipids like other non-steroidal AIs. It is also not liver toxic, and can be ran for longer lengths of ime without negative effect. This makes it a better option to run on cycle from a pure health standpoint. Aromasin will not hurt your gains on cycle like other AIs, but may actually help them. Another benefit on cycle is that steroidal AIs lower SHBG which increases the ratio of free to bound testosterone. What that means during your cycle is a very positive impact on your gains. This (in a sense) makes your Anabolic Androgenic Steroids more bio-available.
 
The half-life of Aromasin is only about 9 hours, and clears quickly. However, ecause of how effective Exemestan is at eliminating Aromatase enzymes
(80-90% after administration), estrogen levels will remain low up to 72 hours after a ingle dose of 25mg. This is why aromasin is very effectively dosed every other day.
In one study, users were still 40% below baseline estrogen values 72 hours after heir dose. This makes aromasin very versatile for dosing and not require more freq-uency.
Now, the place where Aromasin really shines is in post cycle therapy (PCT). There is simply no other Aromatase inhibitor that can compare in terms of its effects on recovery. We already mentioned how Aromasin lowers SHBG, which increases free tes-tosterone.
 
 
Benefits of Exemestan:
 
1. Exemestan lowers estrogen levels in postmenopausal women, which may slow
the growth of certain types of breast tumors that need estrogen to grow in the body.
2. Exemestan is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after surgery, radiation, or other cancer medications have been tried without success.
3. Exemestan may also be used for purposes not listed in this medication guide.
 
Side Effects of exemestan:
 
In bodybuilding and steroid use, side effects with aromasin are rare when taken at an appropriate dosage. Some guys will complain of joint pain from dryness, so when that occurs the dosage should be brought down. Sides among females are much more common because, even though the dosages are similar, the female body will react differently to an AI than a male will. In addition, females will take this drug for a longer period of time when compared to a steroid user. Bottom line is the side effects of not taking an AI for a male on cycle is much more of a risk.
 
 
Exemestan(Aromasin) Dosage:
 
This is dependent on the individual and, also, the amount of aromatizing compounds the person is running. Generally, a good starting dose is 12.5mg ED (every day) or 25mg EOD (every other day). The user must utilize blood work to see how their body is reacting at the starting dosage they choose and then adjust as needed. Experienced anabolic steroid users will usually find a dose they like and stick to it with no problems. As I said already, if you start noticing joint issues then the dose should be lowered; on the other hand, if you start noticing any estrogen related sides, such as puffy or sensitive breasts or water retention, it's time to increase the dosage.
 
 
Pharmaceutical Raw Material  Anti Estrogen Steroids Aromasin CAS107868-30-4
 
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