1.What is Selank?

Selank could be a artificial analogue of the immunomodulatory amide tuftsin; intrinsically, it mimics several of its effects. it's been shown to modulate the expression of Interleukin-6 (IL-6) and have an effect on the balance of T helper cellcytokines. it's been shown to influence the concentration of amine neurotransmitters[2] and induce metabolism of 5-hydroxytryptamine. Selank has conjointly been found to chop-chop elevate the expression of brain-derived tropism issue (BDNF) within the hippocampus of rats.

Selank, also as a connected amide drug, Semax, are found to inhibit enzymes concerned within the degradation of enkephalins and different endogenous regulative peptides, and this action could also be concerned in their effects. it's conjointly been found to have an effect on the activity of carboxypeptidase H and phenylmethylsulfonylfluoride-inhibitedcarboxypeptidase in rat system tissue.

Selank has been found to supply antidepressant-like effects in animal models of depression and psychological state.

2.Clinical trials of Selank

In clinical trials, the drug has shown to produce a sustained nootropic and anxiolytic impact that is helpful for the treatment of generalized folie (GAD).Selank has a plus over ancient anxiety treatments because it has no sedating or negative psychological feature facet effects and no associatedaddiction or withdrawal issues.

Selank is closely associated with another nootropic drug, Semax, conjointly developed by the Institute of genetic science in Russia. This drug is presently out there in Russian and Ukrainian pharmacies.[9]

As with all lipophilized peptides, it wants refrigeration to stay stable inside sterile water solutions, like organic process water concentrations.

3.Selank Basic data.

Product Name: Selank

CAS: 129954-34-3

Sequence: Thr-Lys-PRO-Arg-PRO-Gly-PRO

MF: C33H57N11O9

MW: 751.9

Appearance: White lyophilised Powder

Method of Analysis: HPLC

Use:Reduce stress, relieve depression, sleep disorder quit. Of course, with Selank a puzzle - anxiolytic

Storage: lyophilised peptides though stable at temperature for three months, ought to be hold on desiccated below -18° C. Upon reconstitution of the amide it ought to be hold on at 4° C between 2-21 days and for future use below -18° C.

Packing:as requirments

4.Selank usage

Selank is employed to enhance one's ability to focus and concentrate, scale back mental fatigue, increase mental sharpness and increase memory and learning capability. the primary noticeable impact is sometimes stabilization of mood and general feeling of well-being.

5.How to use it

Injectable Selank use:

duration: from ten days to as long PRN

dosage: between 250 metric weight unit - three mg per day

frequency of injection:1 injection per day for low dose, a pair of injections for higher dose (divided between morning and late afternoon injection).

6.Selank effects

improvement of learning and memory processes (reference, reference)

increased sensory attention

increased curiosity

increased mental clarity

restoration of balance of serotonergic and noradrenergic brain system activity (reference)

anti-anxiety - inhibition of tension (reference)

antiviral activity with no negative effects (reference)

psychostimulant, anti-asthenic - inflated motive (reference)

stabilization of mood and overall feeling of eudaemonia

reversal of psychological state (restoring the sensation of pleasure)

potential restoration of catecholaminergic system functions when harm thanks to habit reference

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