Quick Details:

Lidocaine Hydrochloride
CAS:73-78-9
Synonyms:2-DIETHYLAMINO-N-(2'6'-DIMETHYLPHENYL)ACETAMIDE HCL;2-DIETHYLAMINO-N-[2,6-DIMETHYLPHENYL]ACETAMIDE HCL;ALPHA-(DIETHYLAMINO)-2',6'-ACETOXYLIDIDE HYDROCHLORIDE;A-(DIETHYLAMINO)-2 6-DIMETHYLACETANILIDE HYDROCHLORIDE;LIGNOCAINE HYDROCHLORIDE;LIDOCAINE HYDROCHLORIDE;LIDOCAINE HCL;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamidmonohydrochloride
Formula: C14H23ClN2O
Molecular Weight: 270.7982
EINECS:200-803-8
Product Categories: API;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Research Chemical
Melting point: 75 ~ 79 °C.
Assay: ≥99%
Specifications: 25KG / drum
Appearance: White crystalline powder; Have slightly foul smell or special, bitter, white crystalline powder.

Product description:

Local Anesthetic Drugs Lidocaine, also known as xylocaine and lignocaine , is a medication used to numb tissue in a specific area and to treat ventricular tachycardia . It can also be used for nerve blocks . Lidocaine mixed with a small amount of epinephrine is available to allow larger doses to be used as numbing and to make it last longer . When used as an injectable it typically begins working within four minutes and lasts for half an hour to three hours . Lidocaine may also be applied directly to the skin for numbing.

Common side effects with intravenous use include sleepiness, muscle twitching , confusion , changes in vision , numbness , tingling, and vomiting . It can cause low blood pressure and an irregular heart rate.There are concerns that injecting it into a joint can cause problems with the cartilage . It appears to be generally safe for use in pregnancy . A lower dose may be required in those with liver problems . It is generally safe to use in those allergic to tetracaine or benzocaine . Lidocaine is an antiarrhythmic medication of the class Ib type . Lidocaine works by blocking sodium channels and thus decreasing the rate of contractions of the heart . When used locally as a numbing agent, local neurons cannot signal the brain.

Local Anesthetic Drugs Lidocain was discovered in 1946 and went on sale in 1948 . It is on the WHO Model List of Essential Medicines , the most important medications needed in a basic healthcare system . It is available as a generic medication and is not very expensive . The wholesale cost in the developing world in 2014 was US$0.45 to $1.05 wholesale per 20ml vial of medication .

Applications:

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy . Therefore, lidocaine is suitable for infiltration , block , and surface anesthesia . Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias ; lidocaine , though , has the advantage of a rapid onset of action . Epinephrine vasoconstricts arteries , reducing bleeding and also delays the resorption of lidocaine , almost doubling the duration of anaesthesia . For surface anesthesia, several available formulations can be used for endoscopies , before intubations , etc . Buffering the pH of lidocaine makes local numbing less painful . Lidocaine drops can be used on the eyes for short ophthalmic procedures . There is tentative evidence for topical lidocaine for neuropathic pain.

COA:

How to use Lidocaine Hcl Cream

Before use on the skin, clean and dry the affected area as directed. Apply a thin layer of medication to the affected area of skin, usually 2 to 3 times a day or as directed.

If you are using the spray, shake the canister well before using. While holding the canister 3-5 inches (8-13 centimeters) from the affected area, spray until wet. If the affected area is on the face, spray the medication onto your hand and apply to the face. Do not spray near your eyes, nose, or mouth.

If you are using the foam, shake the canister well before using. Spray the foam onto your hand and apply to the affected area.

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