Human Growth Hormone Releasing Peptides Selank Medicine raw material Lyophilized Peptide
Product Name:Selank
Alias: Selanc
CAS: 129954-34-3
Use:Reduce stress, relieve depression, insomnia quit. Of course, with Selank a puzzle - anxiolytic
Sequence: Thr-Lys-PRO-Arg-PRO-Gly-PRO
MF: C33H57N11O9
MW: 751.9
Purity: 99%
Specification: 5mg/vial
Appearance: White Lyophilized Powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below -18° C.
Packing:as requirments
COA:
Test Items |
Specification |
Test Results |
Description |
White or almost white crystalline powder |
White crystalline powder |
Melting Point |
191.0~193.0ºC |
192ºC |
Loss of drying |
≤1.0% |
0.5% |
Heavy Metal |
≤20ppm |
15ppm |
TLC |
Only one spot |
Only one spot |
Assay |
≥99.5% |
99.91% |
Conclusion |
It complies with the USP 32. |
Description
Selank or selanc is a synthetic heptapeptide analog of the endogenous tetrapeptide tuftsin, with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. Selank is sometimes called tuftsin analog 7. Tuftsin was discovered by Victor Najjar in 1969 (Siemion and Kluczyk, 1999), is produced primarily in the spleen, and is a fraction of Immunoglobulin Gamma (IgG). Selank was first synthesized in Russia as part of efforts to find a "superagonist" version of tuftsin, because tuftsin .
The effects of selank can be divided into two broad categories: neurological and immunomodulatory, with the former coming from selank's effects on BDNF (brain-derived neurotrophic factor) upregulation and enkephalin preservation, and the latter coming from the stimulatory effect of selank on phagocytes, neutrophils, and other immune cells. Selank has shown anxiolytic, nootropic, antidepressant, bacteriocidal, antitumor, and effects in vitro and in vivo as well as promise for various chronic and acute disease states. While selank's actions may be viewed as belonging to two categories, the emerging field of "neuroimmunology" provides new explanations for the effects of immunomodulators on memory and behavior.
Application:
Selank, as well as a related peptide drug, semax, have been found to inhibit enzymes involved in the degradation of enkephalins and other endogenous regulatory peptides, and this action may be involved in their effects.
While Selank is classified as a nootropic-anxiolytic type drug, it uses extend beyond the relief of anxiety and improved cognitive functioning alone. A few areas in which Selank may find itself useful are: Stress reduction, the alleviation of depression, reversal of anhedonia, improvement in mood in emotionally stable individuals, and cessation of insomnia. Of course, with Selank being a nootropic-anxiolytic, it may also prove useful for the treatment of different forms of anxiety, such as G. A. D (generalized anxiety disorder), S. A. D (social anxiety disorder), Panic Disorder, as well as non-diagnosed bouts of anxiety.
As a nootropic, Selank can help enhance mental sharpness, reduce mental fatigue, improve the ability to focus, improve cognitive functioning while in a sleep deficit, and enhance memory.
These effects are provided without the negative side effects typically associated , such as physical dependence, psychological addiction, and decreased motor ability. In fact, Selank is largely devoid of side effects, with the large majority of researchers claiming that it is a "side effect free" compound. This makes Selank more suitable for long-term use.
Usage:
Selank is a synthetic derivative of the human body's naturally produced tetrapeptide Tuftsin. It is a hexapeptide whith a wide range of uses. It was first sinthesized in the late 1990's by the Institute of Molecular Genetics of the Russian Academy of Science. Selank is used as an anxiolytic in the therapy of anxiety and phobic disorders, including generalized anxiety. Its action is similar to that of mild benzodiazepins but without the sedative effects. As a selective anxiolytic with a nootropic component, Selank can be used as treatment of depression, fear and general anxiety. It also reduces phsychic tension. This neuropeptide has passed all phases of clinical trials and is now being prepared for registration and mass production.
Competitive Advantage:
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