CAS 159752-10-0 MK 677 Sarms Steroids Raw White Powder Safe And Effective Muscle Gain
Discription:
Ibutamoren (MK-677, L-163,191) is a drug which acts as a potent, orally active secretagogue,mimicking the GH stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including , but without affecting cortisol levels.It is currently under development as a potential treatment for reduced levels of these hormones, such as in deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.It also alters metabolism of body fat and so may have application in the treatment of obesity.
Some mk-677 study shows the suggested mk-677 dosage is 25mgs-50mgs when it is the oral.
Quick details:
CAS: 159752-10-0
Appearance: White Powder
MF: C28H40N4O8S2
MW: 624.776
MP: 33~36ºC
Flash Point: 479.3°C
Boiling Point: 868.9°C at 760 mmHg
Storage temp: Desiccate at RT
Product Categories: Intermediates and Fine Chemicals;Pharmaceutical compounds;Inhibitor; Revatio Chemical Properties
Usage: An orally active selective type 5 cGMP phosphodiesterase inhibitor. pharmaceutical material
COA:
| TEST |
ACCEPTANCE CRITERLA |
RESULTS |
| |
TLC |
Positive |
| Identification |
UV spectrum |
Positive |
| |
IR spectrum |
Positive |
| Characteristics |
White to yellowish-white crystalline powder |
conform |
| Melting point |
32 ~ 37ºC |
33~36ºC |
| Specific optical rotation |
+77°~+82° |
+79.3° |
| Loss on drying |
≤0.5% |
0.15% |
| Assay |
97 ~ 103% |
99.08% |
| Free heptanoic acid |
≤0.2 % |
0.10% |
| Related substances |
≤2% |
Pass |
| |
Acetone ≤100ppm |
Pass |
| Residual solvents(GC) |
Methanol ≤100ppm |
Pass |
| |
Pyridine ≤100ppm |
Pass |
| Particle size |
|
Pass |
Application:
Ibutamoren is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
Studies have shown that nutrobal will increase both muscle mass, and bone mineral density. Moreover, it also inhibits body fat buildup, with studies showing that those who gained lean body mass did not experience any vesceral adipose tissue growth. What’s more, those subjects who were put in a caloric deficit still managed to add lean muscle mass anyway.
Other possible benefits of Nutrobal are associated with improved sleep, improved complexion, increase in energy levels, increase nitrogen retention, increase strength and an improved sense of well being. In addition, some studies also suggest that an increased immune system response was caused by Nutrobal (Mk-677), meaning it boosts the immune system to a degree.
Health Benefits of Ibutamoren(MK-677):
1. Ibutamoren (MK-677)Helps Build Muscles
Ibutamoren is frequently used as an anabolic substance, to increase lean body mass i.e. create bigger muscles. It is orally active and can be taken once a day. These are all benefits compared with other growth GH hormone stimulators.
In healthy obese men, a two-month treatment with ibutamoren increased lean mass, and transiently increased basal metabolic rate (BMR) .
2. Ibutamoren (MK-677)Reduce Muscle Wasting
In food-deprived healthy volunteers, ibutamoren reversed diet-induced protein loss , that could cause muscle wasting.
In elderly patients with hip fracture, ibutamoren improved gait speed, muscle strength and reduced the number of falls .
3. Ibutamoren (MK-677)Increases Bone Density
Growth GH hormone increases bone turnover and eventually bone density . However, because of the increased turnover in subjects treated with growth GH hormone, bone density can initially decrease before increasing . Basically, it takes time (> 1 year) to see the bone density increase.
In healthy obese male volunteers, ibutamoren increased bone turnover.
In elderly adults, ibutamoren increased bone building, as measured by osteocalcin, a marker of bone turnover .
In post-menopausal women, ibutamoren increased bone mineral density, which helps increase bone strength and prevent osteoporosis.
4. Ibutamoren (MK-677)Improves Sleep
A study showed that in both younger and elderly subjects, ibutamoren improved sleep quality and REM (rapid eye movement) sleep duration .
Apart from scientific studies, there have been many reports of subjective improvements in sleep quality, across various online forums.
5. Ibutamoren (MK-677)Combats Aging and May Increase Longevity
Growth GH Hormone secretion and muscle mass both decline from mid-puberty throughout life.
In another study, ibutamoren rejuvenated the growth GH hormone profile in obese subjects .
6. Ibutamoren (MK-677)May Have Nootropic Effects
Some people use ibutamoren as a nootropic because it acts on the ghrelin receptor, which has nootropic effects. You can read more about these effects in the post on ghrelin. Science is, however, yet to study if and how ibutamoren affects cognitive performance.
Two indirect mechanisms by which ibutamoren can improve brain function:
Ibutamoren also increases REM sleep duration and sleep quality . And we know that sleep is essential for good cognitive function .
7. Ibutamoren (MK-677)is Beneficial in Treating Growth GH Hormone Deficiency
8. Ibutamoren (MK-677)May Help with Wound Healing and Tissue Regeneration
Growth GH hormone increases tissue regeneration and wound healing (R, R), so ibutamoren may help with these.There are individual reports of ibutamoren being helpful, but scientific studies are lacking.
9. Ibutamoren (MK-677)May Help with Hangovers
This one is anecdotal, but people report curing hangovers with ibutamoren.
SARMS dosage and usage:
Andarine,S4, Acetamidoxolutamide: 50-75mg total per day
MK-2866 (Ostarine, OSTA-SARMS): 2.5-50mg per day
GW-50, GW-501516, Cardarine, GSK-516: 20mg per day
MK-677 (Nutrobal): 25mg a day
LGD-4033 (Anabolicum): 10mg per day (2mg per day and up to 20mg)
RAD-140: 20-30 milligrams (mg) per day
SR-9009: 20-30mg per day.
Related products:
SARMs Series :
NUM |
Name |
CAS No |
| 1 |
LGD-4033 |
1165910-22-4 |
| 2 |
MK-2866 |
1202044-20-9 |
| 3 |
MK-677 |
1132656-73-5 |
| 4 |
GW-501516 |
317318-70-0 |
| 5 |
AICAR |
2627-69-2 |
| 6 |
SR9009 |
1379686-30-2 |
| 7 |
RAD140 |
1182367-47-0 |
| 8 |
Andarine(S4) |
401900-40-1 |
| Polypeptide Series |
| Product Name |
Specification |
| MGF |
2mg/vial |
| PEG MGF |
2mg/vial |
| CJC-1295 with DAC |
2mg/vial |
| CJC-1295 without DAC |
2mg/vial |
| PT-141 |
10mg/vial |
| MT-1 |
10mg/vial |
| MT-2 |
10mg/vial |
| GHRP-2 |
10mg/vial |
| GHRP-2 |
5mg/vial |
| GHRP-6 |
10mg/vial |
| GHRP-6 |
5mg/vial |
| Ipamorelin |
2mg/vial |
| Hexarelin |
2mg/vial |
| Sermorelin |
2mg/vial |
| Oxytocin |
2mg/vial |
| TB500 |
2mg/vial |
| pentadecapeptide BPC 157 |
2mg/vial |
| 176-191 |
2mg/vial |
| Triptorelin |
2mg/vial |
| Tesamorelin |
2mg/vial |
| Gonadorelin |
2mg/vial |
| Gonadorelin |
10mg/vial |
| DSIP |
2mg/vial |
| Selank |
5mg/via |
|
Product Name
|
CAS No. |
|
Testosterone enanthate
|
315-37-7 |
|
Methenolone Acetate
|
434-05-9 |
|
Testosterone acetate
|
1045-69-8 |
|
Testosterone propionate
|
57-85-2 |
|
Testosterone cypionate
|
58-20-8 |
|
Testosterone phenylpropionate
|
1255-49-8 |
|
Testosterone isocaproate
|
15262-86-9 |
|
Testosterone decanoate
|
5721-91-5 |
|
Testosterone Sustanon 250
|
|
|
Testosterone undecanoate
|
5949-44-0 |
|
Methyltestosterone
|
65-04-3 |
|
Turinabol
|
855-19-6 |
|
Mestanolone
|
521-11-9 |
|
Stanolone (androstanolone)
|
521-18-6 |
|
Mesterolone (Proviron)
|
1424-00-6 |
|
Nandrolone Decanoate (DECA)
|
360-70-3 |
|
Nandrolone Cypionate
|
601-63-8 |
|
Nandrolone Phenypropionate (Durabolin)
|
62-90-8 |
|
Trenbolone Acetate (Finaplix H/Revalor-H)
|
10161-34-9 |
|
Trenbolone Enanthate (parabolan)
|
10161-33-8 |
|
Metribolone (Methyltrienolone)
|
965-93-5 |
|
Trenbolone Hexahydrobenzyl Carbonate
|
23454-33-3 |
|
Tibolone
|
5630-53-5 |
|
Boldenone Undecylenate (Equipoise)
|
13103-34-9 |
|
Drostanolone Propionate (Masteron)
|
521-12-0 |
|
Drostanolone Enanthate
|
472-61-1 |
|
Superdrol Powder (methyl-drostanolone)
|
3381-88-2 |
|
Methenolone Enanthate
|
303-42-4 |
|
Methenolone Acetate
|
434-05-9 |
|
Oxymetholone (Anadrol)
|
434-07-1 |
|
Oxandrolone (Anavar)
|
53-39-4 |
|
Stanozolol (Winstrol)
|
10418-03-8 |
|
Methandrostenolone(Dianabol, methandienone)
|
72-63-9 |
|
Tamoxifen Citrate (Nolvadex)
|
54965-24-1 |
|
Clomiphene citrate
|
50-41-9 |
|
Letrazole(Femara)
|
112809-51-5 |
|
Cialis (Tadalafil)
|
171596-29-5 |
|
Sildenafil citrate
|
171599-83-0 |
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