Anastrozole Arimidex Anti Estrogen Steroids CAS 120511-73-1 For Anti Cancer

Anastrozole (arimidex) Anti Estrogen Steroids CAS 120511-73-1 for Anti-Cancer

Basic information:

Anastrozole (arimidex)

CAS NO: 120511-73-1
Molecular formula: C17H19N5
Molecular weight: 293.37
Appearance: an off-white color crystalline powder
Storage: Shading, confined preservation
Drug Class: Injectable Anabolic Androgenic Steroid
Standard: Enterprise Standard
Package: 25KG/Drum
Usage: An aromatase inhibitor. Used as an antineoplastic raw materials.
Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer.

Description:

Anastrozole, sold under the brand name Arimidex among others, is a medication used in addition to other treatments for breast cancer. Specifically it is used for hormone receptor-positive breast cancer.It has also been used to prevent breast cancer in those at high risk. It is taken by mouth.

Common side effects include hot flushes, altered mood, joint pain, and nausea. Severe side effects include an increased risk of heart disease and osteoporosis. Use during pregnancy is known to harm the baby. Anastrozole is in the aromatase-inhibiting family of medications. It works by blocking the creation of estrogen.

Anastrozole was patented in 1987 and approved for medical use in 1995. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Anastrozole is available as a generic medication. The wholesale cost in the developing world is about 1.92 to 30.60 USD a month. In the United States the wholesale cost is about 3.81 USD per month.

Mechanism:

Anastrozole works by reversibly binding to the aromatase enzyme, and through competitive inhibition blocks the conversion of androgens to estrogens in peripheral (extragonadal) tissues.

Proper Use:

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance for side effects.

You may take this medicine with or without food.

Anastrozole sometimes causes nausea, vomiting, or diarrhea. However, it is very important that you continue to use the medicine, even if you begin to feel ill. Ask your doctor for ways to prevent these effects or make them less severe.

This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Dosing:

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets):

For breast cancer:

Adults—1 milligram (mg) once a day.
Children—Use and dose must be determined by your doctor.

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