Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity

Basic Information
Place of Origin: China
Brand Name: YW
Certification: ISO9001, KOSHER, USP, GMP
Model Number: 59865-13-3
Minimum Order Quantity: 10 g
Price: Negotiable
Packaging Details: Discreet disguised package or as required
Delivery Time: 2~7 working days
Payment Terms: T/T, , Western Union, MoneyGram, Bitcoin
Supply Ability: 5000kg/week
CAS Number: 59865-13-3 MF: C62H111N11O12
MW: 1202.61 Appearance: White Powder
Purity: ≥98% Usage: Immunosuppressant Drug
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Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 White Powder
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.1,2,3 It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT.1,4,5 Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.
Basic information:
Chemical name: Cyclosporin A
Alternative Name: CsA
Formula: C62H111N11O12
MW: 1202.6
Source: Isolated from Fusarium solani
CAS: 59865-13-3
Purity: ≥98% (Assay)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO (25mg/ml), methanol, 100% ethanol (25mg/ml), acetone or petroleum ether; insoluble in water.
Shipping: Ambient
Long Term Storage: -20°C
Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
CAS No. 79217-60-0;59865-13-3 Outer Packing




Production date 2017.11.09 Shelf life



Standard adopted USP36
Items of analysis Specification Results
Appearance White crystalline powder White crystalline powder
Solubility To comply Complies
Identification To comply Complies
Loss on drying 2.0% max 0.4%
Heavy metals 0.002% max <0.002%
individual impurity 0.7% max 0.39%
sum of all impurity 1.5% max



Any other impurity 0.1% max 0.07%
Acetone 0.5% max 0.29%
Ethanol 0.5% max 0.01%
Ethyl acetate 0.5% max 0.02%
ASSAY 98.5%~101.5% 98.7%
Conclusion Qualified



Medical uses:


Ciclosporin is approved by the FDA to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants.It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis,and as eye drops for treating dry eyes caused by Sjögren's syndrome and meibomian gland dysfunction.


In addition to these indications, ciclosporin is also used in severe atopic dermatitis, Kimura disease, pyoderma gangrenosum, chronic hives, acute systemic mastocytosis, and posterior or intermediate uveitis with noninfective cause.It is also used, albeit infrequently, in severe rheumatoid arthritis and related diseases.


Ciclosporin has also been used in people with acute severe ulcerative colitis and hives that do not respond to treatment with steroids.


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Through 16 years hard work, we have accumulated rich exporting experience to USA, UK, France, Italy, Germany,Spain, Brail, korea, India and so on.We will use special ways to disguise the goods, 98% customs clearance rate is guaranteed, if the delivery is not successful, we will resend for free.


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Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity 0


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