Abortion drug Mifepristone White Raw Powder CAS: 84371-65-3 Pharmaceutical Grade
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome. The two marketed forms of mifepristone are Mifeprex (mifepristone 200mg) and Korlym™ (mifepristone 300mg). Currently under investigation for use in psychotic depression (phase 3 trials).
Chemical name: Mifepristone
Chemical Names: Mifepristone; 84371-65-3; Mifeprex; Mifegyne; RU-486; Mifepriston More...
Molecular Formula: C29H35NO2
Molecular Weight: 429.604 g/mol
Appearance: light yellow powder
Package: 1kg/foil bag
Usage: Abortion drug
|CAS No.||84371-65-3||Outer Packing||1KG/drum|
|Production date||2015.11.04||Shelf life||2018.11.03|
|Standard adopted||CP 2010/Enterprise standard|
|Items of analysis||Specification||Results|
|Description||Light Yellowish Crystalline Powder||Light Yellowish Crystalline Powder|
|Identification||he maximum absorption wavelength of 304nm, 260nm, and infrared absorption spectra were consistent with the control product.||Conformity|
|Specific Rotation||+124°~ +129°||+127.3°|
|Loss On Drying||≤0.5%||0.2%|
Mifepristone followed by a prostaglandin analog (misoprostol or gemeprost) is used for medical abortion.Medical organizations have found this combination to be safe and effective. Guidelines from the Royal College of Obstetricians and Gynaecologists describe medical abortion using mifepristone and misoprostol as effective and appropriate at any gestational age.The World Health Organization and the American Congress of Obstetricians and Gynecologists recommend mifepristone followed by misoprostol for first- and second-trimester medical abortion.Mifepristone alone is less effective, resulting in abortion within 1-2 weeks in 8% to 46% of pregnancies.
See also: Cushing's syndrome
Mifepristone is used for the medical treatment of high blood sugar (hyperglycemia) caused by high cortisol levels in the blood (hypercortisolism) in adults with endogenous Cushing’s syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or cannot have surgery.
Mifepristone is used for emergency contraception.
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