Local Anesthetic Procaine Hydrochloride Powder CAS 51-05-8 2 Years Stability
10 grams
Local Anesthetic Procaine Hydrochloride Powder CAS 51-05-8 2 Years Stability
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Basic Infomation
Place of Origin: China
Brand Name: YW
Certification: GMP, ISO9001, USP, KOSHER
Model Number: 51-05-8
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local anesthetic powder


local anesthetic drugs

Payment & Shipping Terms
Packaging Details: Discreet disguised package or as required
Delivery Time: 3~7 working days
Payment Terms: Western Union, Moneygram, Bitcoin and Bank Wire Transfer
Supply Ability: 5000kg/week
Appearance: White Powder
Assay: Over 99%
Package: 25KG/fiber Drum
CAS Number: 51-05-8
MF: C13H21ClN2O2
MW: 272.77
Product Description

Local anesthetic Drug Procaine hydrochloride CAS: 51-05-8 Raw Powder




Procaine hydrochloride is a salt of the compound Procaine. Procaine is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1. WIF-1 is noted to be reactivated in a cancer cell line and to downregulate the Wnt canonical pathway. In studies utilizing a neuroblastoma cell line (SHEP), Procaine is reported to induce neuronal apoptosis in a manner correlated with lipid solubility of the compound. In an adult mouse muscle cell line (HEK293), the presence of procaine is reported to potently inhibit nicotinic acetylcholine receptors. Procaine is available alone (sc-296134) and in its salt form as Procaine HCl.

Basic information:

Chemical name: Procaine hydrochloride
MF: C13H21ClN2O2
MW: 272.77
CAS: 51-05-8
Appearance: White powder
Purity: 99%
Package: 25KG/fiber drum
Stability: ≥ 2 years




Product name Procaine Hydrochloride
CAS No. 51-05-8 Outer Packing 25KG/drum
Production date 2017.08.25 Shelf life 2020.08.24
Standard adopted USP37
Items of analysis Specification Results
Description A white crystalline powder or colourless crystals Complies
Identification IR Absorption/Reaction of chlorides /Reaction of primary aromatic amines Complies
Melting point 153-158℃ 156.2-157.6℃
Color and clarity of solution Colorless and clear Conforms
Heavy metals ≤0.002% <0.002%
pH (Acidity) 5.0~6.5 (≤0.02NNaOH0.5ml) 5.5/0.2ml
Chromatographic purity ≤0.05%(Sum≤1.0%) Conforms
Loss on drying ≤0.5% 0.16%
Sulphated ash ≤0.1% 0.05%
Assay(C 13 H 20 N 2 O 2 .HCl) 99.0~101.0% 99.8%
Bacterial endotoxins ≤0.6EU/mg <0.6EU/mg
Conclusion ualified




Local anesthesic;Na+ channel blocker
Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.
Non Caine local anesthetic.
A sodium channel blocker and DNA methylation inhibitor





For solution and drug compatibility information, see Compatibility under Stability.

Administer by local infiltration, peripheral nerve block, or subarachnoid (spinal) block.a c d Has been administered by continuous intra-articular infusion† (e.g., for control of postoperative pain); however, such use associated with chondrolysis.200 201 202 203 204 205 206 207 208 209 (See Risk of Chondrolysis Associated with Intra-articular Infusions of Local Anesthetics under Cautions.)

Consult specialized references for specific techniques and procedures for administering local anesthetics.


For local infiltration or peripheral nerve block, inject slowly and avoid rapid injection of large volumes; when feasible, administer in fractional (incremental) doses.

For subarachnoid (spinal) block, use 2-mL single-dose ampuls containing procaine hydrochloride 10% only.c d Position patient properly prior to spinal anesthesia.

For disinfection of container surface, autoclave once at 15 PSI and 121°C for 15 minutesa (diluent dextrose may show some brown discoloration due to caramelization); immersion in antiseptic solution not recommended.c Reautoclaving not recommended because it increases likelihood of crystal formation.



For local infiltration, dilute appropriate dose of 1% procaine hydrochloride injection with 0.9% sodium chloride to obtain final concentration of 0.25 or 0.5%.a d May add 0.5-1 mL of epinephrine 0.1% to each 100 mL of anesthetic solution (to provide final epinephrine concentration of 1:200,000 to 1:100,000) for vasoconstrictive effect.




Product List:


Product name CAS NO. Product name CAS NO.
Benzocaine 94-09-7 Procaine 59-46-1
Hydrochloride 129938-20-1 Tetracaine HCl 136-47-0
Clobetasol Propionate 25122-46-7 L-Thyroxine 51-48-9
Finasteride 98319-26-7 Dydrogesterone 152-62-5
Theophylline 58-55-9/ 5967-84-0 Valdecoxib 181695-72-7
Procaine HCl 51-05-8 Lidocaine HCl 73-78-9
Lidocaine 137-58-6 Benzocaine HCl 23239-88-5
  119356-77-3 L-Epinephrine hydrochloride 55-31-2/ 329-63-5
Chloramphenicol 56-75-7/ 2787-09-9 Doxorubicin hydrochloride 25316-40-9
Omeprazole 73590-58-6/ 119141-89-8 Benzyl benzoate 120-51-4
Dutasteride 164656-23-9 Cyanocobalamin 68-19-9/18195-32-9/ 13408-78-1
Acetaminophen 103-90-2 Paromomycin 7542-37-2
Amikacin disulfate salt 39831-55-5/ 149022-22-0 Nitazoxanide 55981-09-4
Dexamethasone sodium phosphate 55203-24-2/ 312-93-6 Secnidazole 3366-95-8
Trestolone acetate 6157-87-5 Tinidazole 19387-91-8
Lincomycin hydrochloride 7179-49-9 Chlorhexidine Gluconate 18472-51-0
Clotrimazole 23593-75-1 1,3-dimethyl-pentylamine hydrochloride 105-41-9
1,3-Dimethylbutylamine hydrochloride 71776-70-7 4 amino-2-Methylpentane citrate(AMP Citrate) 71776-70-0


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Local Anesthetic Procaine Hydrochloride Powder CAS 51-05-8 2 Years Stability 0


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