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Bodybuilding Sarms Raw Powder GW-501516 Muscle Building Drug CAS 317318-70-0
In terms of obesity, Cardarine (GW-501516) reverses metabolic abnormalities in obese and pre-diabetic men by stimulating fatty acid oxidation. That is, GW-501516 burns fat by increasing glucose uptake in skeletal muscle tissue, which changes the body’s metabolism to burn fat for energy instead of muscle or carbs. Incredibly, it does all this without dropping blood sugar levels like diabetic drugs do. Interestingly, when mice were given a high fat diet, they still lost fat, which proves that cardarine prevents obesity.
CAS NO.: 317318-70-0
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Concerns were raised prior to the 2008 Beijing Olympics that GW501516 could be used by athletes as an ergogenic performance-enhancing drug that was not currently controlled by regulations or detected by standard tests. One of the main researchers from the study on enhanced endurance consequently developed a urine test to detect the drug, and made it available to the International Olympic Committee. The World Anti-Doping Agency (WADA) developed a test for GW501516 and other related PPARδ modulators,and added such drugs to the prohibited list in 2009.
GW501516 has been promoted on bodybuilding and athletics websites and by 2011 had already been available for some time on the black market. In 2011 it was reported to cost $1000 for 10 g.In 2012, WADA recategorised GW501516 from a gene doping compound to a "hormone and metabolic modulator".
GW501516 is the name of a Glaxo Wellcome drug (the GW stands for the company and the number is that of the product). It is also known as GW-501,516, GW1516, GSK-516).
GW-501516 is a selective agonist with high affinity and it is very potent. Various studies on this PPAR receptor in lab rats indicates that it regulates the various proteins that the body uses for energy. Rats with high fat and low metabolism were given the product and they were able to lose weight and to increase overall energy levels.
GW-501516 is often used in two aspects. The first and most common use is that of increased endurance. GW has been banned for professional athletes due to the unfair advantage it provides to endurance athletes. Anyone want a drastic increase in endurance will find that GW truly shines in this aspect. It takes effect very quickly and the results can be staggering. A common dose of 10 mg day will provide a significant increase in endurance.
The second one is that of fat burning. Many users turn to GW as it has shown to melt off fat while still being non-catabolic. You will find that you can still hold on to some muscle as you are losing fat. It helps when you are running it in conjunction with SARMS Ostarine and S4, to hold on to as much muscle as possible. A dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.
Half life, Usage and Dosage:
The normal dose for both men and women are 20 milligrams (mg) per day.
The half life of cardarine is 20-24 hours. This means that once a day dose is totally fine. Some athletes like to use all the 20 mg an hour before their workout session, and others will split the dose in half in the AM and PM.
It is best to squirt the liquid into your mouth, swallow, and then chase down with some juice or water.
Cardarine is used by athletes competing in many different sports. For instance, endurance athletes may increase exercise endurance by stacking this PPAR with the AMP analog drug AICAR, or run cardarine solo. As a result, they will have a greater ability to reach higher RPM’s during their runs without hitting the maximum heart rate. This will allow the runner/cyclist/swimmer to cheat their maximum heart rates and go longer without getting winded, making this stack an incredible weapon to use in endurance sports. Actually, from personal experience I can tell that cardarine can knock over 30-45 seconds off a 5K time if used leading up to a race.
Related SARMs and Usage:
|AICAR||acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown|
|MK2866||medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy.|
|MK-677||A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly|
|LGD-4033||pharmacological profile similar to that of enobosarm, Ostarine,MK-2866|
|GW1516||For obesity, diabetes, dyslipidemia and cardiovascular disease|
|Andarine(S4)||partial agonist, intended mainly for treatment of benign prostatic hypertrophy|
|SR9009||under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice|
|RAD140||New generation for gaining mass and cutting edges|
|YK11||a SARM and myostatin inhibitor in one|
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