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|Purity:||≥98%||Usage:||Treating High Blood Pressure|
local anesthetic powder,
pain relief powder
Valsartan CAS:137862-53-4 Raw Powder for Treating High Blood Pressure
Valsartan (trade name Diovan) is mainly used for treatment of high blood pressure, congestive heart failure, and to increase the chances of living longer after a heart attack. It is an angiotensin II receptor antagonist (commonly called an ARB, or angiotensin receptor blocker), that is selective for the type I (AT1) angiotensin receptor.
Chemical nmae: Valsartan
Appearance: white powder
Purity: over 99%
Usage: Treatment of hypertension
|CAS No.||137862-53-4||Outer Packing||25kg|
|Production date||2017.04.21||Shelf life||2020.04.20|
|Standard adopted||UPS Standard|
|Items of analysis||Specification||Results|
|Description||White or grayish white powder, odorless, slightly hygroscopic||qualified|
|Solubility||Soluble in methanol and ethanol, slightly soluble in ethyl acetate||qualified|
|Identification||IR,HPLC Meet the reference standard||qualified|
|Absorbance at 420nm||≤0.02(at 420nm)||qualified|
|Residue on Ignition||≤0.1%||0.07%|
|Related compounds||Compound A ≤1.0%||0.55%|
|.||Any other individual impunrity ≤0.1%||0.06%|
|.||Total impurity ≤0.3%||0.20%|
|Related Solvents||Ethyl acetate≤50000ppm||3000ppm|
Valsartan is used to treat high blood pressure, congestive heart failure, and to reduce death for people with left ventricular dysfunction after having had a heart attack.
There is contradictory evidence with regard to treating people with heart failure with a combination of an angiotensin receptor blocker like valsartan and an angiotensin-converting enzyme inhibitor, with two major clinical trials (CHARM-additive and ValHeFt) showing a reduction in death, and two others (VALIANT and ONTARGET) showing no benefits, and more adverse effects including heart attacks.
In people with type II diabetes and high blood pressure or albumin in the urine, valsartan is used to slow the worsening and the development end-stage renal disease.
How to use Valsartan:
Read the Patient Information Leaflet if available from your pharmacist before you start taking valsartan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. The dosage is based on your medical condition and response to treatment. For children, the dosage is also based on weight.
If you are using the liquid form of this medication, shake the bottle well for at least 10 seconds before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Tell your doctor if you do not get better or if you get worse (for example, your blood pressure readings remain high or increase).
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