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Pharmaceutical Raw Materials Pain Relieving Anti Inflammatory Medicine Phenacetin CAS 62-44-2

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Pharmaceutical Raw Materials Pain Relieving Anti Inflammatory Medicine Phenacetin CAS 62-44-2

Pharmaceutical Raw Materials Pain Relieving Anti Inflammatory Medicine Phenacetin CAS 62-44-2
Pharmaceutical Raw Materials Pain Relieving Anti Inflammatory Medicine Phenacetin CAS 62-44-2 Pharmaceutical Raw Materials Pain Relieving Anti Inflammatory Medicine Phenacetin CAS 62-44-2

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Product Details:
Place of Origin: CN
Brand Name: YW
Certification: ISO9001,BRC,KOSHER
Model Number: 62-44-2
Payment & Shipping Terms:
Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: Discreet package
Delivery Time: 5-8 working days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000kg/month
Detailed Product Description
CAS: 62-44-2 EINECS: 200-533-0
M.F: C10H13NO2 M.W: 179.2157
Assay: 99% Appearance: White Or Almost White Crystalline Powder
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Manufacturer supply Pharmaceutical Raw Materials,Pain Relieving Anti Inflammatory Medicine Phenacetin CAS:CAS 62-44-2
 
 
Quick Detail:
 
Product Name: Phenacetin
Synonyms: 1-ACETYL-P-PHENETIDIN;4-ACETOPHENETIDIDE;4-acetophenetidine;4'-ETHOXYACETANILIDE;4-ETHOXYACETANILIDE;ACETOPHENETIDIN;ACETOPHENETIDINE;ACET-P-PHENETIDINE
CAS: 62-44-2
MF: C10H13NO2
MW: 179.22
EINECS: 200-533-0
Product Categories: Organics;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs
mp 133-136 °C(lit.)
bp 132 °C / 4mmHg
storage temp. 2-8°C
form powder
Water Solubility 0.076 g/100 mL
Sensitive Hygroscopic
Merck 14,7204
BRN 1869238
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
Chemical Properties white crystalline powder
Usage Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.
Glycosylation inhibitor
 
 
Phenacetin description
 

Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug, which was widely used between its introduction in 1887 and the 1983 ban imposed by the FDA on its use in the United States. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized as paracetamol (acetaminophen), which replaced it in some over-the-counter medications following the ban on phenacetin.


It is also called acetophenetidins. Having glossy leaflets or scales-like crystals that have no odor or taste.Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever, headache, neuralgia and other drugs as a compound agent.

 
 
 
Applications:
 
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).
 
It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.
 
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.
 
 
 
COA:
 
Test Items Specification Test Results
Description Should comply with the standard Pass
Identification Should be positive reaction Pass
  Brownish red 4# Pass
4-chloroacetanilide Should comply with standard Pass
Sulphated ash ≤0.1% 0.06%
Melting point 134ºC to 137ºC 134ºC to 137ºC
Appearance ≥99% 100.58%
Conclusion Complies with BP68 edition
 
 
Phenacetin Function

Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin,
low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic
effect. Because the enzyme inhibitor make Phenacet-Acetate not be converted into paracetamol, still showed
obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The
mild Phenacet-Acetate analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid
coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
 
Shipping & Delivery
 
1.Packages are generally dispatched within approximately 2 days after receipt of payment.
2.After the each shipping we will provide you with:
1) tracking number to track your package online.
2) the few pictures with your order & details.
3.About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.
4.We confirm 99% clearance,100% resending.
5.Is it the best & safest shipping for all our repeat customers!
 
 
Top reason why you choose us ?
 
(1)Fast discreet delivery with great shipping success!
(2)Pictures with your order & details!
(3)We will provide you the tracking number!
(4)Keep track of your goods untill the goods are sent in to your hands.
(5)We confirm 99% clearance,100% resending.
(6)High quality,100% pure products!
(7)Delivery time approx.4-6 business days.
(8)Best, Safe and Secure services.
(9)Customer support 24/7.
 
 
Order infos
 
Payment Methods:West Union,Moeny Gram, Bitcoin and Bank Transfer.
Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
Shipment Time:Within 12 hours after confirmation of your payment
Other Service:Safe shipment,high purity and best price for you.
 
 
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