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Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity

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Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity

Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity
Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity

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Product Details:
Place of Origin: China
Brand Name: YW
Certification: ISO9001, KOSHER, USP, GMP
Model Number: 59865-13-3
Payment & Shipping Terms:
Minimum Order Quantity: 10 g
Price: Negotiable
Packaging Details: Discreet disguised package or as required
Delivery Time: 2~7 working days
Payment Terms: T/T, , Western Union, MoneyGram, Bitcoin
Supply Ability: 5000kg/week
Detailed Product Description
CAS Number: 59865-13-3 MF: C62H111N11O12
MW: 1202.61 Appearance: White Powder
Purity: ≥98% Usage: Immunosuppressant Drug
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local anesthetic powder

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local anesthetic drugs

Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 White Powder
 
Description:
 
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells.1,2,3 It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT.1,4,5 Because of its powerful immunosuppressant activity, cyclosporin A has long been used for the prevention of transplant rejection.
 
Basic information:
 
Chemical name: Cyclosporin A
 
Alternative Name: CsA
 
Formula: C62H111N11O12
 
MW: 1202.6
 
Source: Isolated from Fusarium solani
 
CAS: 59865-13-3
 
Purity: ≥98% (Assay)
 
Appearance: White to off-white powder.
 
Solubility: Soluble in DMSO (25mg/ml), methanol, 100% ethanol (25mg/ml), acetone or petroleum ether; insoluble in water.
 
Shipping: Ambient
 
Long Term Storage: -20°C
 
Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
 
COA:
 
Product name CYCLOSPORINE
CAS No. 79217-60-0;59865-13-3 Outer Packing

 

1KG

 

Production date 2017.11.09 Shelf life

 

2021.10

Standard adopted USP36
Items of analysis Specification Results
Appearance White crystalline powder White crystalline powder
Solubility To comply Complies
Identification To comply Complies
Loss on drying 2.0% max 0.4%
Heavy metals 0.002% max <0.002%
individual impurity 0.7% max 0.39%
sum of all impurity 1.5% max

 

1.43%

Any other impurity 0.1% max 0.07%
Acetone 0.5% max 0.29%
Ethanol 0.5% max 0.01%
Ethyl acetate 0.5% max 0.02%
ASSAY 98.5%~101.5% 98.7%
Conclusion Qualified

 

 

Medical uses:

 

Ciclosporin is approved by the FDA to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants.It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis,and as eye drops for treating dry eyes caused by Sjögren's syndrome and meibomian gland dysfunction.

 

In addition to these indications, ciclosporin is also used in severe atopic dermatitis, Kimura disease, pyoderma gangrenosum, chronic hives, acute systemic mastocytosis, and posterior or intermediate uveitis with noninfective cause.It is also used, albeit infrequently, in severe rheumatoid arthritis and related diseases.

 

Ciclosporin has also been used in people with acute severe ulcerative colitis and hives that do not respond to treatment with steroids.

 

Our Advantages:

 

1. Good reputation:
Our company is a leading chemical company in China, and has more than 16 years history. We have over 10 branch offices, all enjoy good reputation from worldwide customers.

 

2. High Quality&low price
All of our products have top quality and high purity, since we are the factory, our price is competitive.

 

3. Multiple payment methods.
We have mutiple payment methods, T/T, Western Unoin, MoneyGram, and Bitcoin for your convenience.

 

4. Mass Stock
In order to better serve our customers, we are preparing mass stock in our warehouse, we can always ship your parcel within 24 hours.

 

5. High customs clearance pass rate.
Through 16 years hard work, we have accumulated rich exporting experience to USA, UK, France, Italy, Germany,Spain, Brail, korea, India and so on.We will use special ways to disguise the goods, 98% customs clearance rate is guaranteed, if the delivery is not successful, we will resend for free.

 

6. Warm After service.
If you have any problems about the goods, do no hesitate to contact us, we can provide 7/24 service.

 

How to proceed an order:

 

Step 1:when you intended to buy something, pls send me an inquiry by email, skype or whatsapp.
Step2:I will reply you with a quotation as soon as I receive you inquiry.
Step3:we will negotiate products, price, package, payment methods and so on.
Step4:you arrange the payment.
Step5:i will arrange the shipment after receiving you money.
Step6:the tracking number and the picture of the parcel will be sent to you.
Step7:trace the tracking number on website until you receive the goods.
Step8:if you have any questions about the goods, pls contact me, i will try my best to satisfy you.

 

Immunosuppressor Cyclosporin A Raw Powder CAS 59865-13-3 98% High Purity 0

 

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