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|CAS Number:||50-41-9||Names:||Clomiphene Citrate,Clomid|
estrogen blocker supplement,
natural anti estrogen supplements
Clomiphene Citrate White Powder CAS: 50-41-9 Anti-Estrogen Steroid 99% Purity
Appearance: White crystal powder
Package: Foil bag
Clomiphene citrate is anti-estrogen (fertility inducer), such things as dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecological diseases.
Clomiphene citrate is hormone drugs for luteal phase defect, anovulatory infertility, treatment of dysfunctional uterine bleeding embolism.
How Clomiphene Citrate Works in Men?
When men are given Clomid, it blocks the action of estrogen on the pituitary gland, causing an increase in the FSH and LH hormone levels. Higher levels of FSH and LH will boost testosterone production in men, which may improve sperm counts.
If your sperm count is low, Dr Gehlbach may order blood tests to determine if you are a candidate for treatment with Clomid. Usually, the tests will include measurements of FSH, LH, and testosterone levels.
Clomid is an inexpensive option to help improve sperm counts and testosterone levels with relatively few side effects. Some patients experience hot flashes, nausea, dizziness, headaches and temporarily blurred vision. Let Dr. Gehlbach know if you have any unusual symptoms while taking Clomid.
Men who are taking Clomid must take the medication on a daily basis because new sperm is produced every day. The typical dose is one-half a tablet per day, or 25mg of Clomid. While on Clomid, we will regularly check hormone levels to confirm an adequate response to the medication. The dose of Clomid can be custom tailored to the man’s specific needs based upon the lab results. As with any other medicine, it will take time, usually several months, to determine if Clomid is having a beneficial effect on the sperm count.
To understand how clomiphene works, you need to know how the pituitary controls the making of testosterone in the testis. Testosterone is made by Leydig cells in the testis, which I explained in my last post. The pituitary releases a hormone called luteinizing hormone (“LH”) that stimulates the Leydig cells to make testosterone. Testosterone is converted to the female hormone estrogen, (which I also explained in my last post,) and estrogen tells the pituitary to stop making more LH. This kind of negative feedback system is common when it comes to how hormones work. It’s just like a thermostat and heater. As the room gets warmer, the thermostat sends less electricity to the heater. When the room gets colder, the thermostat sends more electricity to the heater.
Clomiphene works by blocking estrogen at the pituitary. The pituitary sees less estrogen, and makes more LH. More LH means that the Leydig cells in the testis make more testosterone.
As I explained in my last post, giving testosterone to a man does just the opposite. The pituitary thinks that the testis is making plenty of testosterone, and LH falls. As a result, the testis stops making testosterone, and the usually high levels of testosterone in the testis fall to the lower level in the blood.
So clomiphene is a way to increase testosterone in the blood and the testis at the same time. It preserves testis size and function while increasing blood testosterone.
Does Clomiphene citrate for men work?
Overall, the success rate for treating male infertility with drugs is lower than the success rate for women. For example, experts expect about 20-25% of men on fertility drugs to fertilize their partner. One study found that a combination of Clomid male infertility treatments and the antioxidant vitamin E boosted sperm count and mobility. And, ultimately, 37% of the partners of the men who took the combination became pregnant, while only 13% of partners with men taking a placebo became pregnant.
Ultimately, the only way to know for sure if Clomid is your fertility solution is to talk to a reproductive specialist. Clomid male infertility treatments may be just what your body needs to start down the path toward conception.
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|Test Items||Specification||Test Results|
|Appearance||White or off-white powder||white powder|
|Water||Not more than 1.0%||0.38%|
|Heavy water||Not more than 0.002%||Conforms|
|Related impuries||Related compound A:Not more than 2.0%||0.86%|
|Individual:Not more than 0.5%||0.38%|
|Conclusion||This batch is complies with USP 32.|
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