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|Assay:||99%||Appearance:||White Or Almost White Crystalline Powder|
local anesthetic powder,
local anesthetic drugs
English name: PHENACETINUM or PHENACETIN
Molecular formula: C10H13NO2
Molecular weight: 179.2158
Category: raw material medicine, antipyretic and analgesic drugs raw materials.
Characteristics: This product is white, there is a flash of scale like crystal or white crystalline powder, no
smell, taste bitter. This product is dissolved in ethanol or chloroform, slightly soluble in boiling water
Soluble in water.
It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or taste. Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever, headache, neuralgia and other drugs as a compound agent.
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin,low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor make phenacetin not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol. Themild phenacetin analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
|Test Items||Specification||Test Results|
|Description||Should comply with the standard||Pass|
|Identification||Should be positive reaction||Pass|
|Brownish red 4#||Pass|
|4-chloroacetanilide||Should comply with standard||Pass|
|Melting point||134ºC to 137ºC||134ºC to 137ºC|
|Conclusion||Complies with BP68 edition|
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