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|CAS:||159752-10-0||Character:||Off- White Powder|
White Powder SARMS Bodybuilding Supplements MK 677 Ibutamoren Mesylate CAS 159752-10-0
Synonyms: Ibutamoren, CHEMBL13817, S1151_Selleck, MK-677
Molecular Weight: 624.77
Molecular Formula: C28H40N4O8S2
Package: Be packed according to the customer requirements and packaging specifications.
Appearance: White crystalline powder
Storage; Store at -20° C
Specificity: MK-677 selectively binds GH secretagogue receptors in certain tissues.
Purity: >99% (HPLC analyzed).
Stability: Store at at 20 °C in dry place until the expiration date.
Source: Chemical Synthesis
Ibutamoren mesylate (MK-677) is an orally active nonpeptide growth hormone (GH) secretagogue. Nutrobal (Mk-677) was found to be very safe. This is an amazing cutting stack with Cardarine and Andarine, which will help melt off the stubborn fat and increase your muscle mass.
MK-677, acts as a potent, orally active growth hormonesecretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.
Ibutamoren is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
Studies have shown that nutrobal will increase both muscle mass, and bone mineral density. Moreover, it also inhibits body fat buildup, with studies showing that those who gained lean body mass did not experience any vesceral adipose tissue growth. What’s more, those subjects who were put in a caloric deficit still managed to add lean muscle mass anyway.
Other possible benefits of Nutrobal are associated with improved sleep, improved complexion, increase in energy levels, increase nitrogen retention, increase strength and an improved sense of well being. In addition, some studies also suggest that an increased immune system response was caused by Nutrobal (Mk-677), meaning it boosts the immune system to a degree.
|AICAR||acts by entering nucleoside pools, significantly increasing levels of adenosine during periods of ATP breakdown|
|MK2866||medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy.|
|MK-677||A growth hormone secretagogue, treatment of obesity, a promising therapy for the treatment of frailty in the elderly|
|LGD-4033||pharmacological profile similar to that of enobosarm, Ostarine,MK-2866|
|GW1516||For obesity, diabetes, dyslipidemia and cardiovascular disease|
|Andarine(S4)||partial agonist, intended mainly for treatment of benign prostatic hypertrophy|
|SR9009||under development at The Scripps Research Institute (TSRI), increases the level of metabolic activity in skeletal muscles of mice|
|RAD140||New generation for gaining mass and cutting edges|
|YK11||a SARM and myostatin inhibitor in one|
5.How it Works:
MK-677 works as growth hormone pulse intensifier, which can be increase through four possible mechanisms:
Increasing the release of GHRH, or “Growth Hormone Releasing Hormone”
Amplifying GHRH signaling in the somatotrophs of the anterior pituitary gland
Reducing somatostatin release, which “turns of” the release of growth hormone; and by
Inhibiting the signaling of the somatostatin receptor
The incredible part being that MK-677 was found to successfully maneuver through all four of these mechanisms. Post-ingestion, growth hormone levels were shown to increase, relative to dosage, starting at 5 mg per day.
Additional benefits include an improvement in bone density so MK677 has the potential to aid with recovery too.
Unlike anabolic steroids, there’s a whole plethora of beneficial side effects including a better complexion, good sleep, heightened energy levels, rise in nitrogen retention, improved immune system response and a general sense of well-being.
For bodybuilders, the benefit to taking MK677 is greater lean mass and lower fat stores.
It also naturally pushes up IGF-1 which increases fat loss and muscle gains, tightens loose skin and heals old injuries, ligaments, tendons and bones. IGF-1 is expensive and difficult to administer, by taking MK677 all the benefits of IGF-1 can be gained, without the same problems or the high cost.
Some of the usual side effects that go with elevated GH levels such as numb hands, some lethargy, as well as slight increased appetite have been reported with the use of Mk-677.Interestingly, during prolonged administration both IGF-1 and GH were increased with no increase in cortisol.Some anecdotal evidence suggested there was a temporary small increase in prolactin when beginning administration, so individuals who are very prone to prolactin side effect may want to incorporate a short schedule of HCGenerate ES to prevent problems. I want to stress, this is only an issue for guys who are extremely prone to prolactin sides, which is usually 1% of users. How do you know if you’re prone to prolactin sides? If you get gynecomastia from taking trenbolone, you’re prone to prolactin sides.
Nutrobal (Mk-677) was found to be very safe and, in fact, showed to reduce tumors in mice, which was hypothesized to be from an increased immune system response.
MK677 is very popular with those who don’t like injections because it has an oral bioavailability. This means it can be taken by mouth without causing any toxicity to the liver, or being metabolized too quickly by the body.
There are liquid and tablets available, both of which are stored at room temperature making it a convenient choice for those who travel.
MK677 is a very safe drug to take, with few contraindications to use.
However, because of its interaction with IGF-1, and the potential to increase cell division, you should take advice from a physician before taking it if you have a history of tumors, growths or cancer.
It’s also not been demonstrated as safe to take for pregnant or breastfeeding women.
There’s no androgenic effects from the use of MK677 which means that it won’t virilize in women.
This means that MK677 is safe for women to take. Similar doses to men can be used, but due to the large amounts of growth hormone produced, starting with 10mg is recommended.
Results have been shown from doses between 5-25mgs a day, dose dependent results should be expected. Higher doses, over 50mgs, have been reported by some, but I don’t see the need to overdo it.
High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity:>=99%
3) We are manufacturer and can provide high quality products with factory price.
Fast and safe delivery:
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate: >=99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
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Question 1 , How do you pack the order ?
Discreet package , the packing suits you best would be choosen to cross customs safely
Question 2 , What is your shipping method ?
Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail
Question 3 , if my order seized by custom ,what do you do ?
Resending police if the tracking number do not update online or it sezied by custom
Questions 4 , What is your payment accept ?
Safe and fast payment :Western Union ,Money Gram ,T/T ,Bitcoin
Questions 5 , Will you supply tracking number ?
Yes ,we supply tracking number for following .In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days
Question 6 , How many days will it take to my country after I do the payment ?
In general ,fastest with 3-5 business , slowest 5-7 business days
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