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α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder

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α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder

China α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder supplier
α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder supplier α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder supplier

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Product Details:

Place of Origin: China
Brand Name: LSW
Certification: USP, GMP, ISO9001
Model Number: 23076-35-9

Payment & Shipping Terms:

Minimum Order Quantity: 10 grams
Price: Negotiate
Packaging Details: Discreet disguised pacakge
Delivery Time: 5~8 working days
Payment Terms: Western union, Moneygram, Bitcoin, Bank wire transfer
Supply Ability: 5000kg/week
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Detailed Product Description
MF: C12H17ClN2S MW: 256.79
Purity: 99% Appearance: White Powder
CAS Number: 23076-35-9 Usage: Veterinary Drug

α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder
 
DESCRIPTION:
 
A solution of ketamine hydrochloride and xylazine hydrochloride has been used together to produce rapid and reversible anesthesia in experimental animals. Xylazine elicited a diuretic response in ketamine-anesthesized animals, probably through activation of complex peripheral and CNS α2-adrenergic receptor systems.
 
Usage Statement:
 
Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
 
Basic information:
 
Product name: Xylazine hydrochloride, alpha2 Adrenoceptor agonist
Description:α2 Adrenoceptor agonist
Biological description: α2 Adrenoceptor agonist (IC50 = 68.2 nM). Ki values for receptor subtypes are 1570 (α2A), 1360 (α2B), 1200 (α2C) and 1460 nM (α2D). Activates KATP channels through the NO/cGMP pathway. Displays anaesthetic, antinociceptive and muscle relaxatory actions.
Purity:> 99%
CAS Number:23076-35-9
Veterinary substance type: Sedative, Anesthestic, Analgesis, Muscle relaxant, Medicinal drug
Substance group: Clonidine analoque
Minimum active substance purity >99%
Substance origin:Synthetic
Mode of action:Inhibits the effects of postganglionic nerve stimulation.
Molecular targets:alpha-2-adrenergic, agonist
EC number: 245-417-0
ATCvet Code: QN05CM92
Therapeutic Class: Nervous system: Psycholeptics
Regulation 37/2010 MRL Classification: Allowed substance (Table 1: Bovine, Equidae)
Molecular mass (g mol-1): 256.79
CAS name: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazine-2-amine hydrochloride
Physical state White crystalline solid
Related substances & organisms
 
COA:
 
Product name

 

Xylazine Hydrochloride

 

CAS No.

 

23076-35-9

 

Outer Packing

 

1KG

 

Production date

 

2018.04.07

 

Shelf life

 

2 years

Standard adopted

 

USP39

Items of analysis Specification Results
Appearance White to almost white crystalline hygroscopic powder White crystalline hygroscopic powder
Identification A: IR absorption B: Thin-layer chromatographic identification test Conforms

 

Loss of drying

NMT 1.0% 0.35%
Melting range 164 ℃ -168 ℃

 

165.4-166.5℃

Heavy metals

 

NMT 20ppm <20ppm
Residue on ignition NMT 0.1% 0.03%
Ph 4~6 4.9
Chromatographic Total impurities: NMT2.0% Conforms
Solution clarity Meet the requirement(CP Standard) Conforms
Toluene NMT890ppm Conforms
Ethanol NMT5000ppm Conforms
N-Butyl alcohol NMT5000ppm Conforms
Assay Not less than 98.0% and not more than 102.0% 99.42%

Conclusion

 

Qualified
 

 

Xylazine HCl Injection Dosage And Administration:

 

1. Dosage: Intravenously - 0.5 mL/100 lbs body weight (0.5 mg/lb). Intramuscularly - 1.0 mL/100 lbs body weight (1.0 mg/lb). Following injection of Xylazine HCl Injection (xylazine) the animal should be allowed to rest quietly until the full effect has been reached. These dosages produce sedation which is usually maintained for 1 to 2 hours, and analgesia which lasts for 15 to 30 minutes.

2. Preanesthetic to Local Anesthesia: Xylazine HCl Injection (xylazine) at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.

 

3. Preanesthetic to General Anesthesia: Xylazine HCl Injection (xylazine) at the recommended dosage rates produces an additive effect to central nervous system depressants such as pentobarbital sodium, thiopental sodium and thiamyl sodium. Therefore, the dosage of such compounds should be reduced and administered to the desired effect. In general, only 1/3 to 1/2 of the calculated dosage of the barbiturates will be needed to produce a surgical plane of anesthesia. Post-anesthetic or emergence excitement has not been observed in animals preanesthetized with Xylazine HCl Injection (xylazine).

 

Xylazine HCl Injection (xylazine) has been used successfully as a preanesthetic agent for pentobarbital sodium, thiopental sodium, thiamylal sodium, nitrous oxide, ether, halothane, glyceryl guaiacolate and methoxyflurane anesthesia.

 

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α2 Adrenoceptor Agonist Xylazine Hydrochloride Veterinary Drug CAS 23076-35-9 White Powder

 

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