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|CAS Number:||23076-35-9||Usage:||Veterinary Drug|
|Items of analysis||Specification||Results|
|Appearance||White to almost white crystalline hygroscopic powder||White crystalline hygroscopic powder|
|Identification||A: IR absorption B: Thin-layer chromatographic identification test||Conforms|
Loss of drying
|Melting range||164 ℃ -168 ℃||
|Residue on ignition||NMT 0.1%||0.03%|
|Chromatographic||Total impurities: NMT2.0%||Conforms|
|Solution clarity||Meet the requirement(CP Standard)||Conforms|
|Assay||Not less than 98.0% and not more than 102.0%||99.42%|
Xylazine HCl Injection Dosage And Administration:
1. Dosage: Intravenously - 0.5 mL/100 lbs body weight (0.5 mg/lb). Intramuscularly - 1.0 mL/100 lbs body weight (1.0 mg/lb). Following injection of Xylazine HCl Injection (xylazine) the animal should be allowed to rest quietly until the full effect has been reached. These dosages produce sedation which is usually maintained for 1 to 2 hours, and analgesia which lasts for 15 to 30 minutes.
2. Preanesthetic to Local Anesthesia: Xylazine HCl Injection (xylazine) at the recommended dosages can be used in conjunction with local anesthetics, such as procaine or lidocaine.
3. Preanesthetic to General Anesthesia: Xylazine HCl Injection (xylazine) at the recommended dosage rates produces an additive effect to central nervous system depressants such as pentobarbital sodium, thiopental sodium and thiamyl sodium. Therefore, the dosage of such compounds should be reduced and administered to the desired effect. In general, only 1/3 to 1/2 of the calculated dosage of the barbiturates will be needed to produce a surgical plane of anesthesia. Post-anesthetic or emergence excitement has not been observed in animals preanesthetized with Xylazine HCl Injection (xylazine).
Xylazine HCl Injection (xylazine) has been used successfully as a preanesthetic agent for pentobarbital sodium, thiopental sodium, thiamylal sodium, nitrous oxide, ether, halothane, glyceryl guaiacolate and methoxyflurane anesthesia.
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