Gamma - Butyrolactone CAS 96-48-0 Reagent Grade For Good Electrical GBL Colorless Clear Oily Liquid

Gamma-Butyrolactone CAS 96-48-0 Reagent Grade for Good Electrical GBL Colorless clear oily liquid 

Basic Information:

Applications:

Addictiveness and dependence

Frequent use of GHB / GBL, even when taken long-term and in moderate doses, does not appear to cause significant physical dependency in the majority of its users. In many people, quitting or temporarily abstaining from use of the drugs is achieved with minimal or no difficulty. However, when consumed in excessive amounts with a high frequency of dosing, physical and psychological dependence can develop. Management of GBL dependence involves considering the person's age, comorbidity and the pharmacological pathways of GBL.

There are some reports of GHB/GBL users adopting a '24/7' dosing regime. This is where the user has become tolerant to the effects of the drug, increasing the dosage and frequency of dosage simply to avoid withdrawal symptoms.

For those users who do report withdrawal symptoms upon quitting the use of GHB / GBL, symptoms seem to depend on the dosage and the length of time the drug was used. Light to moderate users often experience insomnia and sleep - related problems, whereas heavy, prolonged use can cause severe withdrawal symptoms similar to Benzodiazepine withdrawal syndrome.

Description

GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma - hydroxybutyrate, the sodium salt of gamma - hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non - nucleophilic base, like lithium diisopropylamide, GBL can become an alpha - carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.

GBL is not active in its own right; its mechanism of action stems from its identity as a prodrug of GHB. The hypnotic effect of GHB is enhanced by combination with alcohol. A 2003 rat study showed that GBL in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined

GBL is rapidly converted into GHB by paraoxonase ( lactonase ) enzymes, found in the blood. Animals which lack these enzymes exhibit no effect from GBL. GBL is more lipophilic ( fat soluble ) than GHB, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, GBL tends to be more potent and faster - acting than GHB, but has a shorter duration; whereas the related compound 1,4- butanediol ( 1,4- B ) tends to be slightly less potent, slower to take effect but longer - acting than GHB.

 

 

 

Recreationa use:

GBL is a prodrug of GHB. To bypass GHB restriction laws, home synthesis kits were introduced to transform GBL and/or 1,4-B into GHB. GBL can also be used as a recreational drug by itself.

 

 

COA:

 

 

Product Name	γ-Butyrolactone	Quantity	5000kgs
Batch No.	20161025	Packing	200kg per drum
Production date	2016.10.25	Analysis date	2016.10.26
Test Items	Specification		Test Results
Appearance	Clear,Colorless transparent liquid		Clear,Colorless transparent liquid
Water (K.F.) %	≤0.03		0.010
Color Hazen	≤20		6
Density	1.125~1.130		1.127
Refractivity	1.436~1.437		1.4367
Diol(GC) %	≤0.03		0.018
Tetrahydrofuran	≤0.03		0.023
Purity (GC)%	≥99.8%		99.80%
Conclusion(GC) %	this product conforms to Enterprise standard.

 

 

 

 

Shipping & Delivery

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Packing Details

Discreet packing ways as your requirement, 99% go through.

 

Storage

Store in cool and dry area and keep away from direct sunlight.

 

MOQ
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