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Fasoracetam White Powder Cas 110958-19-5 Nootropics Medicine Raw Material
Chemical name: FASORACETAM
Appearance: white powder
Purity: over 99%
Fasoracetam is a research chemical of the racetam family.It is a nootropic, and has been in clinical trials for vascular dementia and attention deficit hyperactivity disorder.
Fasoracetam appears to agonize all three metabotropic glutamate receptors and has improved cognitive function in rodent studies.It is orally available and is excreted mostly unchanged via the urine.
Fasoracetam was discovered by scientists at the Japanese pharmaceutical company Nippon Shinyaku, which brought it through Phase 3 clinical trials for vascular dementia, and abandoned it due to lack of efficacy.
Scientists at Children's Hospital of Philadelphia led by Hakon Hakonarson identified fasoracetam's potential use in attention deficit hyperactivity disorder.Hakonarson started a company called neuroFix Therapeutics, LLC to try to bring the drug to market for this use; neuroFix acquired Nippon Shinyaku's clinical data as part of its efforts.neuroFix was acquired by Medgenics in 2015.Medgenics changed its name to Aevi Genomic Medicine in 2016.Clinical trials in adolescents with ADHD who also have mGluR mutations started in 2016.
Benefits of Fasoracetam:
The benefits of fasoracetam are mostly in anecdote, but there are some studies to suggest a correlation. Given that there are millions of children and adolescents using amphetamine-based ADHD medication, studies testing fasoracetam effects is a good sign. Even better, fasoracetam has made it to phase II and III of clinical trials , which could suggest a high effectiveness for this purpose. As of June 2016, the drug was still in these trials.
According to anecdotal evidence on fasoracetam benefits, the concentration and stimulation benefits are moderate. One person likened the stimulation effects to noopept and another said it was more of an energy boost than stimulation.
Aside from these focus and concentration related benefits, there is evidence for neuroprotective effects as well. One rat study showed that fasoracetam could prevent memory disruptions. This is common amongst the racetam line of drugs and makes sense that fasoracetam would display many of these same properties.
Another interesting benefit of fasoracetam is as an antidepressant and anxiolytic. A study of rats with learned helplessness showed that the drug had potent antidepressant effects without some of the side effects (such as MAOI interactions). This study concluded that GABA (B) up-regulation was able to increase test results in the animals.
How Does Fasoracetam Work?
There is no conclusive evidence as to how fasoracetam works to improve cognition, but theories suggest it interacts with the cholinergic system and receptors of GABA and glutamate.
The GABA (B) up-regulation discussed in the benefits is another mechanism of action for the antidepressant and anxiety related benefits, but more information is needed to fully understand how fasoracetam works regarding memory formation and stimulation.
There is no standardized dose of fasoracetam for humans yet. The anecdotal evidence suggests smaller doses range around 10 - 15 mg with larger doses in the 30 - 50 mg per serving three times per day.
The latter heavy dose was used by someone who tried using GABA up-regulation to resolve phenibut withdrawal symptoms, however.
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