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Nootropic supplement Adrafinil White Powder CAS 63547-13-7 Purity 99%
Chemical name: ADRAFINIL
Appearance: white powder
Purity: over 99%
Adrafinil is a nootropic supplement with a difference: it’s a CNS stimulant that can prevent fatigue, increase energy, and enhance wakefulness, but it doesn’t cause anxiety or other typical stimulant side effects.It may also improve mood, focus, and learning ability,and may even help keep your brain healthy.
Adrafinil is also different in that it’s a prodrug, a biologically inactive compound that is converted to an active drug inside the body. When Adrafinil is metabolized, it is converted to modafinil,a stimulant that increases wakefulness and has a pronounced eugeroic effect without the corresponding increase in anxiety and hyperactivity that is typical of amphetamine stimulants.
Adrafinil is very structurally similar to its close chemical cousin and bioactive metabolite, modafinil. The only structural difference is that terminal amide hydroxyl group of adrafinil ((diphenylmethyl)sulﬁnyl-2 acetohydroxamic acid) is lacking in modafinil (diphenylmethyl)sulﬁnyl-2 acetamide).
The mechanism of adrafinil appears to rely on postsynaptic α-adrenergic activity since an increase in locomotion caused by adrafinil is blocked by prazosin (α1 antagonist), yohimbine (α2 antagonist), or phenoxybenzamine (mixed α-antagonist).These increases through adrenergic neurotransmission are thought to be responsible for adrafinil's energetic properties.
Orally ingested adrafinil may undergo one of two metabolic results. The main metabolite is the active modafinil, which is itself metabolized to the inactive modafinilic acid, then modafinil sulfone. Adrafinil, however, can also be metabolized to inactive modafinilic acid without conversion to modafinil. This may account for its lower potency.
Dosage recommendations vary, but a range of 150 to 300 mg daily is widely accepted as safe and effective. It is a very powerful nootropic, so it’s a good idea to give the body a chance to adjust by starting with a lower dose and gradually increasing it as needed.
Adrafinil should be ingested on an empty stomach. Because of its potent wakefulness-inducing properties, it should be taken in the morning to allow for normal night’s sleep. Effects can typically be felt within an hour, and the duration of a single dose can be 3-4 hours.
Taking adrafinil on a long-term basis is inadvisable, as it could potentially affect liver function. Using adrafinil in a cycle (for instance, two weeks on, one week off) is preferable. If you do plan to take adrafinil for an extended period, it’s important to have your liver function closely monitored by a medical professional.
Adrafinil works efficiently on its own, but it also stacks very well with other nootropics, such as piracetam, phenylpiracetam, and Noopept.
Adrafinil and Noopept Stack
Stacking adrafinil with Noopept is a popular combination that is suited for extended periods of mental work where focus and attention are needed.
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|Product name||CAS number|
|Beta nicotinamide mononucleotide||1094-61-7|