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Nootropics Drug Galantamine Hydrobromide CAS 1953-04-4 for Treating Alzheimer's
Chemical name: Galantamine Hydrobromide
Class: Parasympathomimetic (Cholinergic) Agents
Chemical Names: (4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef]benzazepin-6-ol hydrobromide
Molecular Formula: C17H21N03.HBr
CAS Number: 1953-04-4
Appearance: white powder
Purity: over 99%
What is galantamine?
release oral capsule. It’s also available as a generic or the brand-name drugs Razadyne and Razadyne ER. Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name versions.
Galantamine may be used as part of a combination therapy. That means you need to take it with other drugs to treat dementia associated with Alzheimer’s Disease.
Uses in mythology:
In Homer's Odyssey the god Hermes gives Odysseus an herb with "a black root, but milklike flower" called "moly", which Hermes claims will make Odysseus immune to the sorceress Cerce's drugs. It is believed that moly is the snowdrop Galanthus nivalis, which is a source of galantamine.The descriptions of moly given by Greek physician and herbalist Dioscorides support moly's identity as Galanthus nivalis.It has been proposed that the drugs Cerce used were an extract from Datura stramonium (also known as jimsonweed), which causes memory loss and delirium.This would give a basis for the snowdrop's use as an antidote, as Datura stramonium is anticholinergic, while galantamine is an acetylcholinesterase inhibitor.
Galantamine is indicated for the treatment of mild to moderate vascular dementia and Alzheimer's.In the United States, it is approved by the Food and Drug Administration as safe and effective for the treatment of mild to moderate dementia.As with other cholinesterase inhibitors, galantamine may not be effective for treating mild cognitive impairment.
How it works:
Galantamine belongs to a class of drugs called cholinesterase inhibitors. A class of drugs refers to medications that work similarly. They have a similar chemical structure and are often used to treat similar conditions.
The cause of Alzheimer’s disease isn’t fully understood. People with this disease have low amounts of a chemical acetylcholine in their brains. A decreased amount of acetylcholine has been linked to dementia. Galantamine works to prevent the breakdown of acetylcholine. This increases the concentration of the chemical in the brain, and may help decrease the symptoms of dementia.
This drug may not work as well when Alzheimer’s disease gets worse. There is no evidence that galantamine prevents Alzheimer’s disease from getting worse.
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