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Anti-Infection Drug Doxycycline hyclate Powder CAS: 24390-14-5
Doxycycline hyclate (Vibramycin, Periostat, Vibra-Tabs, Acticlate) is a moderately priced drug used to treat many kinds of infections, like dental, skin, respiratory, and urinary tract infections. It also treats acne, Lyme disease, malaria, and certain sexually transmitted diseases. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions. Generic doxycycline hyclate is covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can offset the cost.
Chemical name: Doxycycline hyclate
Appearance: White powder
Purity: over 99%
|Product name||Doxycycline hyclate|
|CAS No.||24390-14-5,10592-13-9||Outer Packing||25kg|
|Production date||20170215||Shelf life||20200214|
|Items of analysis||Specification||Results|
|Characters||Yellow crystalline powder||Complies|
|Specific Absorbance||300-335at 349nm,calculated on the Anhydrous,ethanol-free substance||322 322|
|Specific optical rotation||-105°～-120°||-111°|
|Light absorbing impurities||Not more than 0.07 at 490nm,calculated on the anhydrous,ethanlo-free substance||0.02|
|Metacycline||Not More Than 2.0%||0.21|
|6-epidoxycycline||Not More Than 2.0%||1.92|
|Oxytetracycine||Not More Than 0.5%||0.04|
|4-epidoxycycline||Not More Than 0.5%||0.04|
|4,6-epidoxycycline||Not More Than 0.5%||N.D.|
|Impurity F||Not More Than 0.5%||0.31|
|Any other impurities||Not More Than 0.5%||0.01|
Generic 100 mg doxycycline capsules
In addition to the general indications for all members of the tetracycline antibiotics group, doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease,acne, rosacea,and rickettsial infections.
In Canada, in 2004, doxycycline was considered a first-line treatment for chlamydia and non-gonococcal urethritis and with cefixime for uncomplicated gonorrhea.
It is used in prophylaxis against malaria. It should not be used alone for initial treatment of malaria, even when the parasite is doxycycline-sensitive, because the antimalarial effect of doxycycline is delayed. This delay is related to its mechanism of action, which is to specifically impair the progeny of the apicoplast genes, resulting in their abnormal cell division.
It can be used in a treatment plan in combination with other agents, such as quinine.
Moraxella catarrhalis, Brucella melitensis, Chlamydia pneumoniae, and Mycoplasma pneumoniae are generally susceptible to doxycycline, while some Haemophilus spp., Mycoplasma hominis, and Pseudomonas aeruginosa have developed resistance to varying degrees.
It is used in the treatment and prophylaxis of anthrax and Leptospirosis.It is also effective against Yersinia pestis (the infectious agent of bubonic plague), and is prescribed for the treatment of Lyme disease,ehrlichiosis and Rocky Mountain spotted fever.
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