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Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage

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Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage

China Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage supplier
Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage supplier Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage supplier

Large Image :  Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage

Product Details:

Place of Origin: China
Brand Name: LSW
Certification: GMP, ISO9001, USP, KOSHER
Model Number: 581-08-8

Payment & Shipping Terms:

Minimum Order Quantity: 10 grams
Price: Negotiable
Packaging Details: Discreet disguised package or as required
Delivery Time: 3~7 working days
Payment Terms: Western Union, Moneygram, Bitcoin and Bank Wire Transfer
Supply Ability: 5000kg/week
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Detailed Product Description
Appearance: White Powder Assay: Over 99%
Usage: Local Anesthesia CAS Number: 581-08-8
MF: C10H13NO2 MW: 179.22
High Light:

local anesthetic powder

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pain relief powder

Pain Killer Pharmacy White Powder Phenacetin CAS: 581-08-8 with 99% Purity

 

Description:

 

Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug, which was widely used between its introduction in 1887 and the 1983 ban imposed by the FDA on its use in the United States. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized as paracetamol (acetaminophen), which replaced it in some over-the-counter medications following the ban on phenacetin.

 

Specification:

 

Chemical name: Phenacetin
Synonyms: N-(4-Ethoxyphenyl)acetamide; p-Acetophenetidide; 4-(Acetylamino)phenetole; 4-Ethoxy-1-acetylaminobenzene; 4-Ethoxyacetanilide; 4’-Ethoxyacetanilide; Aceto-4-phenetidine; Acetophenetidin; Acetophenetidine; Acetophenetin; Acetphenetidin; Fenidina; Fenina; Kalmin; N-Acetyl-4-ethoxyaniline; N-Acetyl-p-ethoxyaniline; N-Acetyl-p-phenetidine; NSC 7651; Pertonal; Phenacetine; Phenazetin; Phenedina; Phenidin; Phenin; p-Ethoxyacetanilide;
CAS Number: 581-08-8
Molecular form: C10H13NO2
Appearance: White Solid
Melting Point: 134-136°C
Mol. Weight: 179.22
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine.
Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.

 

Background:

 

Phenacetin, introduced in 1887, was used principally as an analgesic, and was the first NSAID and fever reducer to go on the market. Typical doses of 300mg to 500mg a day result in an analgesic effect. Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action of the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type), intercostal neuralgia, and some forms of ataxia.

Phenacetin, and products containing phenacetin have been shown in an animal model to be carcinogenic. In humans, many case reports have implicated products containing phenacetin in urothelial neoplasms, especially transitional cell carcinoma of the renal pelvis. In one prospective series, phenacetin was associated with an increased risk of death due to urologic or renal diseases, death due to cancers, and death due to cardiovascular diseases.


In addition, people with glucose-6-phosphate dehydrogenase deficiency may experience acute hemolysis while taking this drug. Acute hemolysis is possible in the case of patients who develop an IgM response to Phenacetin leading to immune complexes that bind to erythrocytes in blood. The erythrocytes are then lysed when the complexes activate the complement cascade.

Phenacetin was widely used until the third quarter of the twentieth century, but was then largely replaced by non-carcinogenic drugs. Some branded phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Both propyphenazone and paracetamol are metabolites of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.

 

In Norway phenacetin is sold perscription over-the-counter with caffeine in a preparation know as Fenazon-Koffein. One tablet of Fenazon-Koffein contains 500mg phenacetin and 100mg caffeine along with filler products such as glucose.

 

How It Works:

 

Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.

It is metabolised in the body as paracetamol (acetaminophen).

 

Dosage:

 

Analgesic mixtures containing phenacetin were previously marketed as tablets or capsules containing between 150 and 300 mg phenacetin. Common combinations were: 150 mg phenacetin, 230 mg aspirin, and 15 or 30 mg caffeine; or 150 mg phenacetin, 230 mg aspirin, 30 mg caffeine, and 8, 15, 30, or 60 mg codeine phosphate. Phenacetin alone was also available in 250 and 300 mg doses as tablets, and up to 500 mg doses as powder. The usual dose was 300 mg 4-6 times per day, and the daily dose was not to exceed 2 g

 

 

 

Product List:

 

Benzocaine CAS:94-09-7
Benzocaine hydrochloride CAS:23239-88-5
Tetracaine hydrochloride CAS:136-47-0
Procaine CAS:59-46-1
Tetracaine CAS:94-24-6
Pramoxine Hydrochloride CAS:637-58-1
Procaine HCl CAS:51-05-8
Lidocaine CAS:137-58-6
Dibucaine hydrochloride CAS:61-12-1
Prilocaine CAS:721-50-6
Propitocaine hydrochloride CAS:1786-81-8
Proparacaine hydrochloride CAS:5875-06-9
Lidocaine hydrochloride CAS:73-78-9
Articaine hydrochloride CAS:23964-57-0
Levobupivacaine hydrochloride CAS:27262-48-2
Ropivacaine hydrochloride CAS:132112-35-7
Bupivacaine CAS:2180-92-9
Bupivacaine hydrochloride CAS:14252-80-3

 

Top reason why you choose us ?

 

(1) Fast discreet delivery with great shipping success!
(2) Pictures with your order & details!
(3) We will provide you the tracking number!
(4) Keep track of your goods untill the goods are sent in to your hands.
(5) We confirm 99% clearance,100% resending.
(6) High quality,100% pure products!
(7) Delivery time approx.4-6 business days.
(8) Best, Safe and Secure services.
(9) Customer support 24/7.

 

Shipping & Delivery:

 

1. Packages are generally dispatched within approximately 2 days after receipt of payment.
2. After the each shipping we will provide you with:
1) a link & tracking number to track your package online.
2) the few pictures with your order & details.
3. About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.
4. We confirm 99% clearance,100% resending.
5. Is it the best & safest shipping for all our repeat customers!

 

Pain Killer Pharmacy White Phenacetin Powder CAS 581-08-8 Local Anesthesia Usage

 

 

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